1887

Abstract

No DNA polymerase I-like activity was found associated with the ultraviolet (u.v.)-protecting plasmids R205. R46 or pKM101 in either uninduced or u.v.-induced wild-type or DNA polymerase I-deficient strains of Nor was any plasmid-associated polymerase activity detectable in similar systems containing u.v.-irradiated DNA as template. However, plasmids R205, R46 and pKM101 still increased survival and mutagenesis of the polymerase I-deficient strain after u.v. irradiation.

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/content/journal/micro/10.1099/00221287-125-1-131
1981-07-01
2021-05-14
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References

  1. Anderson E. S., Datta N. 1965; Resistance to penicillins and its transfer in Enterobacteriaceae. Lancet 1:407–409
    [Google Scholar]
  2. Bachmann B. J. 1972; Pedigrees of some mutant strains of Escherichia coli K-12. Bacteriological Reviews 36:525–557
    [Google Scholar]
  3. Bowerstock D., Moses R. E. 1973; Ultraviolet irradiation inhibition of replicative deoxyribonucleic acid synthesis in toluene-treated Escherichia coli. Journal of Biological Chemistry 248:7449–7455
    [Google Scholar]
  4. Davis B. D., Mingioli E. S. 1950; Mutants of Escherichia coli requiring methionine or vitamin B12. Journal of Bacteriology 60:17–28
    [Google Scholar]
  5. Fowler R. E., Mcginty L., Mortelmans K. E. 1979; Spontaneous mutational specificity of drug resistance plasmid pKM101 in Escherichia coli. Journal of Bacteriology 140:929–937
    [Google Scholar]
  6. Gefter M. L., Hirota Y., Kornberg T., Wechsler J. A., Barnoux C. 1971; Analysis of DNA polymerases II and III in mutants of Escherichia coli thermosensitive for DNA synthesis. Proceedings of the National Academy of Sciences of the United States of America 683150–3153
    [Google Scholar]
  7. Kato T., Shinoura Y. 1977; Isolation and characterization of mutants of Escherichia coli deficient in induction of mutations by ultraviolet light. Molecular and General Genetics 156:121–131
    [Google Scholar]
  8. Kronish J. W., Walker G. C. 1979; The effects of the ultraviolet-protecting plasmids pKM101 and R205 on DNA polymerase I activity in Escherichia coli K-12. Mutation Research 60:135–142
    [Google Scholar]
  9. Lackey D., Walker G. C., Keng T., Linn S. 1977; Characterization of an endonuclease associated with the drug resistance plasmid pKM101. Journal of Bacteriology 134:583–588
    [Google Scholar]
  10. Lehrbach P., Kung A. H. C., Lee B. T. O., Jacoby G. A. 1977a; Plasmid modification of radiation and chemical-mutagen sensitivity in Pseudomonas aeruginosa. Journal of General Microbiology 98:167–176
    [Google Scholar]
  11. Lehrbach P., Kung A. H. C., Lee B. T. O. 1977b; Loss of ultraviolet light protection and enhanced ultraviolet light-induced mutability in Pseudomonas aeruginosa carrying mutant R plasmids. Journal of General Microbiology 101:135–141
    [Google Scholar]
  12. Macphee D. G. 1972; Effect of an R factor on resistance of Salmonella typhimurium to radiation and chemical treatment. Mutation Research 14:450–453
    [Google Scholar]
  13. Macphee D. G. 1974; DNA polymerase activity determined by the ultraviolet-protecting plasmid, R- Utrecht. Nature, London 251:432–434
    [Google Scholar]
  14. Monk M., Kinross J. 1972; Conditional lethality of recA and recB derivatives of a strain of Escherichia coli K-12 with a temperature-sensitive deoxyribonucleic acid polymerase I. Journal of Bacteriology 109:971–978
    [Google Scholar]
  15. Monk M., Peacy M., Gross J. D. 1971; Repair of damage induced by ultraviolet light in DNA polymerase-defective Escherichia coli cells. Journal of Molecular Biology 58:623–630
    [Google Scholar]
  16. Monti-Bragadin C., Babudri N., Samer L. 1976; Expression of the plasmid pKMlOl- determined DNA repair system in recA~ and lex~ strains of Escherichia coli. Molecular and General Genetics 145:303–306
    [Google Scholar]
  17. Moody E. E. M., Low K. B., Mount D. W. 1973; Properties of strains of Escherichia coli K12 carrying mutant lex and rec alleles. Molecular and General Genetics 121:197–205
    [Google Scholar]
  18. Mortelmans K. E., Stocker B. A. D. 1976; Ultraviolet light protection, enhancement of ultra-violet light mutagenesis and mutator effect of plasmid R46 in Salmonella typhimurium. Journal of Bacteriology 128:271–282
    [Google Scholar]
  19. Mortelmans K. E., Stocker B. A. D. 1979; Segregation of the mutator property of plasmid R46 from its ultraviolet-protecting property. Molecular and General Genetics 167:317–327
    [Google Scholar]
  20. Tweats D. J., Pinney R. J., Smith J. T. 1974; R-factor mediated nuclease activity involved in thymineless elimination. Journal of Bacteriology 118:790–795
    [Google Scholar]
  21. Tweats D. J., Thompson M. J., Pinney R. J., Smith J. T. 1976; R factor-mediated resistance to ultraviolet light in strains of Escherichia coli deficient in known repair functions. Journal of General Microbiology 93:103–110
    [Google Scholar]
  22. Upton C., Pinney R. J. 1979; Absence of plasmid-mediated DNA polymerase activity from UV-induced strains of Escherichia coli. Journal of Pharmacy and Pharmacology 31:35P
    [Google Scholar]
  23. Villani G., Boiteux S., Radman M. 1978; Mechanism of ultraviolet-induced mutagenesis: ex-tent and fidelity of in vitro DNA synthesis on irradiated templates. Proceedings of the National Academy of Sciences of the United States of America 753037–3041
    [Google Scholar]
  24. Volkert M. R., Spencer D. F., Clark A. J. 1979; Indirect and intragenic suppression of the lexA102 mutation in Escherichia coli B/r. Molecular and General Genetics 177:129–137
    [Google Scholar]
  25. Walker G. C. 1977; Plasmid (pKMlOl)-mediated enhancement of repair and mutagenesis: dependence on chromosomal genes in Escherichia coli K-12. Molecular and General Genetics 152:93–103
    [Google Scholar]
  26. Walker G. C., Dobson P. P. 1979; Mutagenesis and repair deficiencies of Escherichia coli umuC mutants are suppressed by the plasmid pKM101. Molecular and General Genetics 172:17–24
    [Google Scholar]
  27. Witkin E. M. 1976; Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli. Bacteriological Reviews 40:869–907
    [Google Scholar]
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