@article{mbs:/content/journal/micro/10.1099/00221287-123-2-383, author = "Lienert, Ingrid and Richter, Dietmar", title = "Sringent Control in an Extreme Thermophilic Bacterium. Preliminary Characterization of a Guanosine 3′,5′-Polyphosphate [(p)ppGpp] Synthesizing Enzyme from Thermus thermophilus", journal= "Microbiology", year = "1981", volume = "123", number = "2", pages = "383-386", doi = "https://doi.org/10.1099/00221287-123-2-383", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-123-2-383", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "A guanosine 3′,5′-bis(diphosphate) (ppGpp) and guanosine 3′-diphosphate 5′-triphosphate (pppGpp) synthesizing enzyme is present in the ribosomal fraction of Thermus thermophilus. The enzyme is comparable to the Escherichia coli (p)ppGpp synthetase I (stringent factor) in that it requires ribosomes, mRNA and codon-specific, uncharged tRNA. The ribosomal complex can be replaced by methanol. Ribosomes from Escherichia coli do not function as effectors of the Thermus thermophilus enzyme.", }