%0 Journal Article %A Vives-Rego, J. %A Juárez, A. %A Imperial, J. %A Parés, R. %T Correlation Between Isocitrate Dehydrogenase Activity and Glutamate Excretion by Citrobacter intermedius C3 %D 1981 %J Microbiology, %V 122 %N 1 %P 167-170 %@ 1465-2080 %R https://doi.org/10.1099/00221287-122-1-167 %I Microbiology Society, %X Glutamic acid was excreted by Citrobacter intermedius strain C3. which carries the extrachromosomal S factor, but not by strains lacking S factor. There was a correlation between the isocitrate dehydrogenase activity of cell-free extracts and the rate of glutamate excretion by various strains. Differences were detected in the Km for isocitrate, the specific activity and stability of isocitrate dehydrogenase from strains CBC356 and C3 which differ in their ability to excrete glutamate. We suggest that the S factor plasmid is required for isocitrate dehydrogenase synthesis in C. intermedius C3 and that this enzyme plays an important role in the regulation of glutamate excretion. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-122-1-167