1887

Abstract

Glucosamine acted as a gratuitous catabolite repressor of maltose utilization in This repression was relieved in a linear manner as the maltose concentration was increased. Three mutants were isolated in which maltose utilization was no longer repressed by glucosamine. One of these mutants may be generally deficient in catabolite repression since it was not defective in glucosamine transport but was insensitive to glucosamine repression on all catabolite repressible carbon sources tested. Each mutant possessed a maltose uptake system which was notably less sensitive to glucose repression than that of the wild-type strain. These results are discussed in terms of a proposed model for regulation of maltose utilization in

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-121-2-479
1980-12-01
2021-05-11
Loading full text...

Full text loading...

/deliver/fulltext/micro/121/2/mic-121-2-479.html?itemId=/content/journal/micro/10.1099/00221287-121-2-479&mimeType=html&fmt=ahah

References

  1. Furst A., Michels C. A. 1977; An evaluation of d-glucosamine as a gratuitous catabolite repressor of Saccharomyces carlsbergensis. Molecular and General Genetics 155:309–314
    [Google Scholar]
  2. GÖrts C. P. M. 1969; Effect of glucose on the activity and the kinetics of the maltose-uptake system and of α-glucosidase in Saccharomyces cerevisiae. Biochimica et biophysica acta 184:299–305
    [Google Scholar]
  3. Khan N. A., Eaton N. R. 1971; Genetic control of maltose formation in yeast. I. Strains producing high and low basal levels of enzyme. Molecular and General Genetics 112:317–322
    [Google Scholar]
  4. Scott T. A., Hockney R. C. 1979; Synthesis of vitamin B6 by a mutant of Escherichia coli K12 and the action of 4′-deoxypyridoxine. Journal of General Microbiology 110:285–289
    [Google Scholar]
  5. Stewart G. G., Erratt J., Garrison I., Goring T., Hancock I. 1979; Studies on the utilization of wort carbohydrates by brewer’s yeast strains. Master Brewers of the Americas Technical Quarterly 16:1–7
    [Google Scholar]
  6. Ten Berge A. M. A., Zoutewelle G., Van De Poll K. W. 1973; Regulation of maltose fermentation in Saccharomyces carlsbergensis. I. The function of the gene MAL6 as recognised by mal6 mutants. Molecular and General Genetics 123:233–246
    [Google Scholar]
  7. Van Rijn J., Van Wijk R. 1972; Differential sensitivities of the two malate dehydrogenases and the maltose permease to the effect of glucose in Saccharomyces carlsbergensis. Journal of Bacteriology 110:477–484
    [Google Scholar]
  8. Van Wijk R., Ouwehand J., Van Den Bos T., Koningsberger V. V. 1969; Induction and catabolite repression of α-glucosidase synthesis in protoplasts of Saccharomyces carlsbergensis. Biochimica et biophysica acta 186:178–191
    [Google Scholar]
  9. Zimmermann F. K., Eaton N. R. 1974; Genetics of induction and catabolite repression of maltose synthesis in Saccharomyces cerevisiae. Molecular and General Genetics 134:261–272
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-121-2-479
Loading
/content/journal/micro/10.1099/00221287-121-2-479
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error