From a strain carrying , a mutation giving rise to asporogeny, a revertant was isolated which sporulated at about 10 of the wild-type frequency but in which the time-course of sporulation was much protracted. Genetic analysis of this revertant showed that it retained but had acquired a secondary mutation failed to suppress mutations in or ; it also failed to suppress another mutation in the locus. is extremely closely linked (recombination frequency ≤ 1%) with the mutation that it specifically suppresses. Strains carrying alone sporulated at a frequency at least two orders of magnitude below that in the double mutant. It is suggested that and lead to compensating amino acid changes in the protein specified by the locus.


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