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Transport of radioactively labelled peptides has been used to characterize a common transport system for di- and tripeptides in Candida albicans. This permease is energy-dependent and has a requirement for l-amino acid residues, an α-linkage between residues and a free amino terminus. Transport was followed by the accumulation inside the cell of intact peptides and component amino acids. After transport of glycyl-[U-14C]phenylalanine the radioactive material was accumulated inside the cell and subsequently leaked into the medium under certain conditions.
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