1887

Abstract

Viomycin and capreomycin, antibiotics produced by and respectively, are potent inhibitors of bacterial protein synthesis. Although these organisms are highly tolerant of their own products , their ribosomes are fully sensitive to the action of the drugs However, they possess novel, antibiotic-inactivating enzymes (viomycin phosphotransferase, capreomycin phosphotransferase, capreomycin acetyl-transferase) which, in addition to possible biosynthetic roles, may contribute to the resistances observed

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1980-09-01
2024-04-16
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