%0 Journal Article %A Creaser, E. H. %T The Induced (Adaptive) Biosynthesis of β-Galactosidase in Staphylococcus aureus %D 1955 %J Microbiology, %V 12 %N 2 %P 288-297 %@ 1465-2080 %R https://doi.org/10.1099/00221287-12-2-288 %I Microbiology Society, %X SUMMARY: Staphylococcus aureus strain Duncan readily synthesized the adaptive (inducible) enzyme β-galactosidase in washed suspension when supplied with a mixture of amino acids and an inducer. The amount of enzyme produced was a function of the quantity of amino acids supplied and the rate of synthesis was determined by the concentration of inducer in the system. Galactose was a highly active inducer, lactose a relatively feeble one. Production of the enzyme ensued after a lag period which could be shortened by the addition of glucose or sodium lactate and further shortened by supplying a mixture of purines and pyrimidines to the system. Enzyme formation was strongly inhibited by various antibacterial agents. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-12-2-288