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Volume 12, Issue 2

The Differences in Antibiotic Sensitivity of Closely Related Single Cells of Free

Abstract

SUMMARY:Evidence is offered that when a single bacterial cell divides the daughter cells are frequently unlike one another. This can be demonstrated by separating cells, allowing them to divide and then transferring individuals derived from them to agar containing a suitable concentration of antibiotic. Differences between single cells can be tested by four criteria: (1) division; (2) growth without division: (3) ability to resume division when transferred back to normal broth; (4) failure to lyse.

  • Published Online:
© Society for General Microbiology 1955
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/content/journal/micro/10.1099/00221287-12-2-269
1955-04-01
2025-04-30
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/content/journal/micro/10.1099/00221287-12-2-269
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The Differences in Antibiotic Sensitivity of Closely Related Single Cells of Proteus vulgaris
Microbiology 12, 269 (1955); https://doi.org/10.1099/00221287-12-2-269
/content/journal/micro/10.1099/00221287-12-2-269
/content/journal/micro/10.1099/00221287-12-2-269
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