1887

Abstract

Summary: A study has been made of the effects of post-irradiation treatment of ultraviolet irradiated spores of sp. strain T12 with distilled water, iodoacetate and a peptone medium.

At doses exceeding 400 ergs/mm. (which exceed that corresponding to the peak of the dose/variant-frequency curve) treatment in distilled water results in increases in both the proportion of survivors and the frequency of variants amongst the survivors. Treatment with iodoacetate caused larger increases, whereas treatment with peptone medium suppressed the increases. A partial resolution of the lethal and mutagenic effects of the radiation was obtained at lower doses, for it was possible to modify the proportion of survivors without changing the variant frequency.

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/content/journal/micro/10.1099/00221287-12-1-1
1955-02-01
2021-08-03
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References

  1. Hollaender A., Emmons C.W. 1941; Wavelength dependence of mutation production in the ultraviolet with special emphasis on fungi. Cold Spr. Harb. Symp. quant. Biol. 9:179
    [Google Scholar]
  2. Hollaender A., Stapleton G.E., Billen D. 1953; The reduction of radiation damage to living cells by treatment after exposure. Abstracted in Science 117:468
    [Google Scholar]
  3. Jacob F., Siminovitch L., Wollman E. 1952; Sur la biosynthese d’une colicine et sur son mode d’action. Ann. Inst. Pasteur 83:295
    [Google Scholar]
  4. Lwoff A. 1952; Cycle du bactériophage chez une bactérie lysogene.Bull. World Hlth Org. 6:249
    [Google Scholar]
  5. Lwoff A. 1953; L’induction. Ann. Inst. Pasteur, 84:225
    [Google Scholar]
  6. Newcombe H.B. 1953; Radiation-induced instabilities in Streptomyces. J. gen. Microbiol. 9:30
    [Google Scholar]
  7. Stapleton G.E., Billen D., Hollaender A. 1952; Recovery of aj-irradiated bacteria at suboptimal incubation temperatures. Bad. Proc. 158:
    [Google Scholar]
  8. Wainwright S.D., Mullaney J. 1953; Some effects of metabolic inhibitors upon survival of ultra-violet irradiated Escherichia coli. Experientia 9:376
    [Google Scholar]
  9. Wainwright S.D., Nevill A. 1955; Induction of provariants as a function of dose of ultra-violet radiation. J. gen. Microbiol. 12:13
    [Google Scholar]
  10. Witkin E.M. 1953; Effects of temperature on spontaneous and induced mutations in Escherichia coli. Proc. not. Acad. Sci., Wash. 39:427
    [Google Scholar]
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