1887

Abstract

The influence of a prior period of thymine and amino acid deprivation on the restoration of DNA synthesis and on the fraction of cells surviving after u.v. irradiation and subsequent incubation with chloramphenicol in B/r Hcrhas been studied. Thymine and amino acid deprivation stimulated post-irradiation DNA synthesis and increased the fraction of surviving cells if, in the period between deprivation and u.v. irradiation, protein synthesis occurred. It is concluded that proteins induced by thymine starvation participated in the repair of u.v.-irradiated cells.

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/content/journal/micro/10.1099/00221287-119-2-527
1980-08-01
2022-01-27
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References

  1. Bhattacharjee S. B., Das J. 1973; Strand breaks in deoxyribonucleic acid of thymine- starved bacteria.. International Journal of Radiation Biology 23:167–174
    [Google Scholar]
  2. Billen D. 1969; Replication of the bacterial chromosome, location of new initiation sites after irradiation.. Journal of Bacteriology 97:1169–1175
    [Google Scholar]
  3. Bridges B. A. 1972; Evidence for a further dark- repair process in bacteria.. Nature New Biology 240:52–53
    [Google Scholar]
  4. Brozmanová J., Mašek F., Sedliaková M. 1978; Photoreactivation of thymine dimers in thymine- and tryptophan-starved Escherichia coli B/r Hcr+ and Her.. Studia biophysica 20:221–228
    [Google Scholar]
  5. Doudney C. O. 1973; Chloramphenicol effect on DNA replication on UV-damaged bacteria.. Mutation Research 17:1–12
    [Google Scholar]
  6. Drakulic M., Errera M. 1959; Chloramphenicol-sensitive DNA synthesis in normal and irradiated bacteria.. Biochimica et biophysica acta 31:459–463
    [Google Scholar]
  7. Ghosh N., Bhattacharjee S. B. 1975; Photoreactivation of thymine starved Escherichia coliBg−1.. Photochemistry and Photobiology 21:1–4
    [Google Scholar]
  8. Gudas L. J., Pardee A. B. 1975; Model for regulation of Escherichia coli DNA repair functions.. Proceedings of the National Academy of Sciences of the United States of America 72:2330–2334
    [Google Scholar]
  9. Gudas L. J., Pardee A. B. 1976; DNA synthesis inhibition and the induction of protein X in Escherichia coli.. Journal of Molecular Biology 101:459–477
    [Google Scholar]
  10. Hanawalt P. C., Cooper P. K. 1971; Determination of repair replication in vivo.. Methods in Enzymology 12:221–230
    [Google Scholar]
  11. Harold F. M., Ziporin Z. Z. 1958; Synthesis of protein and DNA in Escherichia coli irradiated with ultraviolet light.. Biochimica et biophysica acta 29:439–440
    [Google Scholar]
  12. Kogoma T., Connaughton M. J. 1978; Induced stable DNA replication as a possible SOS function.. 7th Annual ICN-UCLA Symposium on Molecular and Cellular Biology Keystone, Colorado: Abstract 159.
    [Google Scholar]
  13. Kogoma T., Lark K. G. 1970; DNA replication in Escherichia coli: replication in absence of protein synthesis after replication inhibition.. Journal of Molecular Biology 52:143–164
    [Google Scholar]
  14. Kogoma T., Lark K. G. 1975; Characterization of the replication of Escherichia coli DNA in the absence of protein synthesis: stable DNA replication.. Journal of Molecular Biology 94:243–256
    [Google Scholar]
  15. Little J. W., Hanawalt P. C. 1977; Induction of protein X in Escherichia coli.. Molecular and General Genetics 150:237–248
    [Google Scholar]
  16. Nakayama H., Hanawalt P. 1975; Sedimentation analysis of deoxyribonucleic acid from thymine-starved Escherichia coli.. Journal of Bacteriology 121:537–547
    [Google Scholar]
  17. Radman M. 1975; SOS repair hypothesis; phenomology of an inducible DNA repair which is accompanied by mutagenesis.. In Molecular Mechanisms for Repair of DNA pp. 355–367 Hanawalt P., Setlow R. B. Edited by New York:: Plenum Press.;
    [Google Scholar]
  18. Sedliaková M., Slezáriková V. 1977; Involvement of UV-induced protein in the reinitiation of DNA replication in UV-irradiated Escherichia coli.. Folia microbiologica 22:313–316
    [Google Scholar]
  19. Sedliaková M., Slameňová D., Štukovsky′ R. 1966; Changes in the radioresistance of bacteria after the inhibition of proteosynthesis in the preirradiation phase.. Folia microbiologica 11:169–172
    [Google Scholar]
  20. Sedliaková M., Mašek F., Brozmanová J. 1972; Thymine-dimer excision after the preirradiation inhibition of DNA synthesis.. FEBS Letters 23:325–326
    [Google Scholar]
  21. Sedliaková M., Mašek F., Brozmanová J., Mašková L., Bugán J., Slezáriková V. 1973; Depression of thymine dimer excision without an adequate effect on survival in Escherichia coli B/r Hcr+ cells.. Neoplasma 20:499–510
    [Google Scholar]
  22. Sedliaková M., Mašek F., Brozmanová J., Mašková L., Slezáriková V. 1974; Depression of thymine dimer excision in various excision-proficient strains of Escherichia coli.. Biochimica et biophysica acta 349:442–446
    [Google Scholar]
  23. Sedliaková M., Brozmanová J., Slezáriková V., Mašek F., Fandlová E. 1975; Function of the UVR marker in dark repair of DNA molecules.. Neoplasma 22:361–384
    [Google Scholar]
  24. Sedliaková M., Slezáriková V., Mašek F., Brozmanová J. 1978; UV-inducible repair; influence on survival, dimer excision, DNA replication and breakdown in Escherichia coliB/r Hcr+ cells.. Molecular and General Genetics 160:81–87
    [Google Scholar]
  25. Walker J. R. 1970; Thymine starvation and single-strand breaks in chromosomal deoxyribonucleic acid of Escherichia coli.. Journal of Bacteriology 104:1391–1392
    [Google Scholar]
  26. Witkin E. M. 1976; Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli.. Bacteriological Reviews 40:869–907
    [Google Scholar]
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