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The β-lactam antibiotic cephalosporin C has been extracted and partially purified from liquid cultures of the fungi Emericellopsis salmosynnemata and Acremonium kiliense. The ability of these and certain other fungi to lyse cyanobacteria is attributable to the production of this antibiotic. This is supported by the similarities, seen in light and electron microscopic preparations, of Anabaena flos-aquae cells exposed to pure cephalosporin C and to fungal exudates.
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