1887

Abstract

We have previously described a large family of mutants of which were selected by continuous culture on xylitol and which superproduce ribitol dehydrogenase. One of these strains was found to harbour a high copy number 2·1 × 10 dalton plasmid. This plasmid is a deletion derivative of a low copy number 3·5 × 10 dalton plasmid present in the ancestral strain of However, since these plasmids do not contain the genes required for pentitol catabolism and some enzyme-superproducing strains have lost all DNA homologous to the plasmids, they are not implicated in the fast growth on xylitol. The plasmids contain regions of homology with the plasmid ColE 1.

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1980-05-01
2021-07-27
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