Phenotypic Resistance to Miconazole and Amphotericin B in Candida albicans

E. F. Gale; Alison M. Johnson; D. Kerridge; Frances Wayman

doi:10.1099/00221287-117-2-535

Phenotypic Resistance to Miconazole and Amphotericin B in Candida albicans

E. F. Gale, Alison M. Johnson, D. Kerridge and Frances Wayman
First Published: 01 April 1980 https://doi.org/10.1099/00221287-117-2-535

Abstract

SUMMARY: Phenotypic resistance to both amphotericin B and miconazole develops in stationary phase cultures of Candida albicans and this resistance lies in changes in the cell wall. Study of the effects of growth conditions, treatment with SH-reactive agents and treatment with enzymes indicates that the nature of the changes leading to resistance must be different for the two drugs.

Received: 02/08/1979
Published Online: 01/04/1980

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Microbiology

Volume 117, Issue 2

Short Communication

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Phenotypic Resistance to Miconazole and Amphotericin B in Candida albicans

Abstract

Most read this month

Most cited this month Most Cited RSS feed

Metals, minerals and microbes: geomicrobiology and bioremediation

Generic Assignments, Strain Histories and Properties of Pure Cultures of Cyanobacteria

CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies

Short motif sequences determine the targets of the prokaryotic CRISPR defence system

Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin

Quantification of biofilm structures by the novel computer program comstat

Distribution of Menaquinones in Actinomycetes and Corynebacteria

Long-term impacts of antibiotic exposure on the human intestinal microbiota

Autotrophic growth of anaerobic ammonium-oxidizing micro-organisms in a fluidized bed reactor

Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones