Phenotypic Resistance to Miconazole and Amphotericin B in Candida albicans

E. F. Gale; Alison M. Johnson; D. Kerridge; Frances Wayman

doi:10.1099/00221287-117-2-535

Phenotypic Resistance to Miconazole and Amphotericin B in Candida albicans

E. F. Gale, Alison M. Johnson, D. Kerridge and Frances Wayman
First Published: 01 April 1980 https://doi.org/10.1099/00221287-117-2-535

Abstract

SUMMARY: Phenotypic resistance to both amphotericin B and miconazole develops in stationary phase cultures of Candida albicans and this resistance lies in changes in the cell wall. Study of the effects of growth conditions, treatment with SH-reactive agents and treatment with enzymes indicates that the nature of the changes leading to resistance must be different for the two drugs.

Received: 02/08/1979
Published Online: 01/04/1980

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Microbiology

Volume 117, Issue 2

Short Communication

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Phenotypic Resistance to Miconazole and Amphotericin B in Candida albicans

Abstract

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