1887

Abstract

Two nystatin-resistant mutants of were isolated and identified as and Analysis of the sterol composition of these cells indicated a total absence of ergosterol and an increased level of a possible precursor. Successive cultures of the resistant strains in a medium supplemented with 10 g ergosterol ml induced in 5 d a sensitivity to nystatin identical to that of the wild-type strain. These ergosterol-supplemented strains had an ergosterol content similar to that of the wild-type strain cultured in the absence of ergosterol. Resistance to nystatin was recovered after 5 d subculture in medium without ergosterol.

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/content/journal/micro/10.1099/00221287-117-1-249
1980-03-01
2021-05-10
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