1887

Abstract

Mitochondria prepared from grown on low concentrations of glucose bound less carbodiimide than mitochondria from grown on high concentrations of glucose. This decreased binding could be prevented by including cycloheximide in the growth medium. These phenomena are discussed in terms of a possible mechanism of carbodiimide inhibition of energy-linked reactions.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-116-1-233
1980-01-01
2024-10-03
Loading full text...

Full text loading...

/deliver/fulltext/micro/116/1/mic-116-1-233.html?itemId=/content/journal/micro/10.1099/00221287-116-1-233&mimeType=html&fmt=ahah

References

  1. Azzi A., Bragadin M.A., Tamburro A.M., Santato M. 1973; Site directed spin labelling of the mitochondrial membrane. Journal of Biological Chemistry 248:5520–5526
    [Google Scholar]
  2. Broughall J.M. 1973 The biochemistry of oligomycin resistance in mutants of the yeast Saccharomyces cerevisiae. Ph.D. thesis University of Warwick:
    [Google Scholar]
  3. Godin D.V., Schrier S.L. 1970; Mechanism of inactivation of erythrocyte membrane adenosine triphosphatase by carbodiimides. Biochemistry 9:4068–4077
    [Google Scholar]
  4. Griffiths D.E., Houghton R.L. 1974; Studies on energy linked reactions: modified mitochondrial ATPase of oligomycin resistant mutants of Saccharomyces cerevisiae. European Journal of Biochemistry 46:157–167
    [Google Scholar]
  5. Holloway C.T., Roberton A.M., Knight I.G., Beechey R.B. 1966; The binding of [14C]-dicyclohexylcarbodiimide to mitochondrial fractions. Biochemical Journal 100:79P
    [Google Scholar]
  6. Knight I.G., Holloway C.T., Roberton A.M., Beechey R.B. 1968; The chemical nature of the site of action of dicyclohexylcarbodiimide in mitochondria. Biochemical Journal 109:27P
    [Google Scholar]
  7. Partis M.D., Bertoli E., Mascarello S., Griffiths D.E. 1975; The organisation of oligomycin sensitive ATPase. Biochemical Society Transactions 4:88–91
    [Google Scholar]
  8. Roberton A.M., Holloway C.T., Knight I.G., Beechey R.B. 1968; A comparison of the effects of N,N′-dicyclohexylcarbodiimide, oligomycin and aurovertin on energy linked reactions in mitochondria and submitochondrial particles. Biochemical Journal 108:445–456
    [Google Scholar]
  9. Sebald W., Sebald-Althaus M., Lukins H.B., Wachter E. 1978; Biogenesis of the mito-chondrial ATPase complex: the dual origins of subunits and genes. In The Membrane ATPases (in the Press) Peeters H. Edited by Gent: European Press.;
    [Google Scholar]
  10. Wachter E., Sebald W., Tzagoloff A. 1977; Altered amino acid sequence of the DCCD binding protein in the oli-1 resistant mutant D273-10b/A21 of Saccharomyces cerevisiae. . In Mitochondria 1977 pp. 441–449 Bandlow W., Schweyen R.J., Wolf K., Kaudewitz F. Edited by Berlin: Walter de Gruyter.;
    [Google Scholar]
  11. Wickerham L.J. 1946; A critical evaluation of the nitrogen assimilation tests commonly used in the classification of yeasts. Journal of Bacteriology 52:293–301
    [Google Scholar]
/content/journal/micro/10.1099/00221287-116-1-233
Loading
/content/journal/micro/10.1099/00221287-116-1-233
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error