@article{mbs:/content/journal/micro/10.1099/00221287-115-1-207, author = "Luengo, Jose M. and Revilla, GloriA and Villanueva, Julio R. and Martin, Juan F.", title = "Lysine Regulation of Penicillin Biosynthesis in Low-producing and Industrial Strains of Penicillium chrysogenum", journal= "Microbiology", year = "1979", volume = "115", number = "1", pages = "207-211", doi = "https://doi.org/10.1099/00221287-115-1-207", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-115-1-207", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "The inhibitory effect of l-lysine on penicillin biosynthesis by Penicillium chrysogenum has been compared in a low-producing strain (Wis. 54–1255) and a high-producing strain (AS-P-78). Lysine inhibited total penicillin synthesis to a similar extent in both strains. However, in the high-producing strain the onset of penicillin synthesis occurred even at a high lysine concentration, whereas in the low-producing strain lysine had to be depleted before penicillin production commenced.", }