Differing Contribution of Polymorphonuclear Cells and Macrophages to Protection of Mice against and Free

Abstract

Bacterial growth and lethality of in mice were augmented by car-rageenan-treatment and X-irradiation (8 J kg), whereas growth and lethality of were augmented by X-irradiation but not by carrageenan-treatment. Protection against at least in the early phases, appears to depend mainly on macrophages, since carrageenan depletes macrophages but not polymorphonuclear cells (PMN), whereas protection against appears to depend mainly on PMN. Ineffectiveness of PMN in elimination of is supported by histological examination and observation of intracellular killing

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1979-11-01
2024-03-29
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