1887

Abstract

The virulence of five strains of as judged by their ability to survive in the respiratory tract and induce pneumonia in CBA mice, was related to the ability of viable organisms to persist in the peritoneal cavity. This appeared to be the result of differences in the ability of the strains to resist killing by peritoneal macrophages It is suggested that resistance to phagocytosis by macrophages is an important determinant of virulence for

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1979-10-01
2021-10-23
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References

  1. Allison A.C., Harington J.S., Birbeck M. 1966; An examination of the cytotoxic effects of silica on macrophages. Journal of Experimental Medicine 124:141–154
    [Google Scholar]
  2. Brownlie J., Howard C.J., Gourlay R.N. 1976; Pathogenicity of certain mycoplasma species in the bovine mammary gland. Research in Veterinary Science 20:261–266
    [Google Scholar]
  3. Cassell G.H., Lindsey J.R., Overcash R.G., Baker H.J. 1973; Murine mycoplasma res-piratory disease. Annals of the New York Academy of Sciences 225:395–412
    [Google Scholar]
  4. Cole B.C., Ward J.R. 1973; Interaction of Mycoplasma arthritidis and other mycoplasmas with murine peritoneal macrophages. Infection and Immunity 7:691–699
    [Google Scholar]
  5. Dajani A.S., Clyde W.A., Denny F.W. 1965; Experimental infection with Mycoplasma pneumoniae (Eaton’s agent). Journal of Experimental Medicine 121:1071–1086
    [Google Scholar]
  6. Glynn A.A. 1972; Bacterial factors inhibiting host defence mechanisms. Symposia of the Society for General Microbiology 22:75–112
    [Google Scholar]
  7. Green G.M., Kass E.H. 1964; The role of the alveolar macrophage in the clearance of bacteria from the lung. Journal of Experimental Medicine 119:167–176
    [Google Scholar]
  8. Howard C.J., Gourlay R.N., Brownlie J. 1973; The virulence of T-mycoplasmas, isolated from various animal species, assayed by intramammary inoculation in cattle. Journal of Hygiene 71:163–170
    [Google Scholar]
  9. Howard C.J., Taylor G., Collins J., Gourlay R.N. 1976; Interaction of Mycoplasma dispar and Mycoplasma agalactiae subsp.bo vis with bovine alveolar macrophages and bovine lacteal polymorphonuclear leucocytes. Infection and Immunity 14:11–17
    [Google Scholar]
  10. Howard C.J., Stott E.J., Taylor G. 1978; The effect of pneumonia induced in mice with Mycoplasma pulmonis on resistance to subsequent bacterial infection and the effect of a respiratory infection with Sendai virus on the resistance of mice to Mycoplasma pulmonis. . Journal of General Microbiology 109:79–87
    [Google Scholar]
  11. Jones T.C., Hirsch J.G. 1971; The interaction in vitro of Mycoplasma pulmonis with mouse peritoneal macrophages and l-cells. Journal of Experimental Medicine 133:231–259
    [Google Scholar]
  12. Jones T.C., Yeh S., Hirsch J.G. 1972; Studies on attachment and ingestion phases of phagocytosis of Mycoplasma pulmonis by mouse peritoneal macrophages. Proceedings of the Society for Experimental Biology and Medicine 139464–470
    [Google Scholar]
  13. Kessel R.W.I., Monaco L., Marchiso M.A. 1963; The specificity of the cytotoxic action of silica - a study in vitro.. British Journal of Ex-perimental Pathology 44:351–364
    [Google Scholar]
  14. Lipman R.P., Clyde W.A. 1969; The inter-relationship of virulence, cytadsorption, and peroxide formation in Mycoplasma pneumoniae.. Proceedings of the Society for Experimental Biology and Medicine 1311163–1167
    [Google Scholar]
  15. Lipman R.P., Clyde W.A., Denny F.W. 1969; Characteristics of virulent, attenuated and avirulent Mycoplasma pneumoniae strains. Journal of Bacteriology 100:1037–1043
    [Google Scholar]
  16. Organick A.B., Siegesmund K.A., Lutsky 1.1. 1966; Pneumonia due to mycoplasma in gnotobiotic mice. II. Localisation of Mycoplasma pulmonis in the lungs of infected gnotobiotic mice by electron microscopy. Journal of Bacteriology 92:1164–1176
    [Google Scholar]
  17. Powell D.A., Clyde W.A. 1975; Opsonin reversible resistance of Mycoplasma pneumoniae to in vitro phagocytosis by alveolar macrophages. Infection and Immunity 11:540–550
    [Google Scholar]
  18. Razin S. 1978; The mycoplasmas. Microbiological Reviews 42:414–470
    [Google Scholar]
  19. Rowley D., Whitby J.L. 1959; The bactericidal activity of mouse macrophages in vitro.. British Journal of Experimental Pathology 40:507–515
    [Google Scholar]
  20. Simberkoff M.S., Elsbach P. 1971; The interaction in vitro between polymorphonuclear leucocytes and mycoplasma. Journal of Experimental Medicine 134:1417–1430
    [Google Scholar]
  21. Smith G.R. 1968; Factors affecting bacteriaemia in mice inoculated with Mycoplasma mycoides var.mycoides.. Journal of Comparative Pathology 78:267–274
    [Google Scholar]
  22. Smith H. 1978; Microbial surfaces in relation to pathogenicity. Bacteriological Reviews 41:475–500
    [Google Scholar]
  23. Stuart A.E. 1967; Techniques for the study of phagocytes. In Handbook of Experimental Immunology pp. 1034–1053 Edited by Weir D. M. Oxford & Edinburgh: Blackwell Scientific Publications;
    [Google Scholar]
  24. Taylor G. 1975 Studies on immune mechanisms in Mycoplasma infections Ph.D. thesis University of London;
    [Google Scholar]
  25. Taylor G., Howard C.J., Gourlay R.N. 1977; Protective effect of vaccines on Mycoplasma pulmonis induced respiratory disease of mice. Infection and Immunity 16:422–431
    [Google Scholar]
  26. Tully J.G. 1969; Murine mycoplasmas. In The Mycoplasmatales and l-phase of Bacteria pp. 571–605 Edited by Hayflick L. Amsterdam: North Holland Publishing Co.;
    [Google Scholar]
  27. Whitby J.L., Rowley D. 1959; The role of macrophages in the elimination of bacteria from the mouse peritoneum. British Journal of Experimental Pathology 40:358–370
    [Google Scholar]
  28. Whittlestone P. 1972; Pathogenicity of myco-plasmas in animals. Symposia of the Society for General Microbiology 22:217–250
    [Google Scholar]
  29. Zisman B., Hirsch M.S., Allison A.C. 1970; Selective effects of anti-macrophage serum, silica and anti-lymphocyte serum on pathogenesis of Herpesvirus infection of young adult mice. Journal of Immunology 104:1155–1159
    [Google Scholar]
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