1887

Abstract

Summary: Neutralization by specific antibody of a fast-killing variant strain of which showed high spontaneous infectivity for cell monolayers, was examined. It appeared that in spontaneous infection antibody-treated chlamydiae were neutralized by inhibition of attachment to cells. Centrifugation imposed a different effect: infection was inhibited at some step at or subsequent to attachment.

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1979-09-01
2024-04-25
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References

  1. Ainsworth S., Allan I., Pearce J. H. 1976; Neutralisation and adherence of chlamydiae to mucous surfaces. Proceedings of the Society for General Microbiology 414–15
    [Google Scholar]
  2. Allan I., Pearce J. H. 1979; Modulation by centrifugation of cell susceptibility to chlamydial infection. Journal of General Microbiology 111:87–92
    [Google Scholar]
  3. Allan I., Spragg S. P., Pearce J. H. 1977; Pressure and directional force components in centrifuge-assisted chlamydial infection of cell cultures. FEMS Microbiology Letters 2:79–82
    [Google Scholar]
  4. Blyth W. A., Taverne J. 1974; Neutralisation of TRIC organisms by antibody: enhancement by antisera prepared against immunoglobulins. Journal of Hygiene, Cambridge 72:129–134
    [Google Scholar]
  5. Blyth W. A., Reeve P., Graham D. M., Taverne J. 1962; The production of antisera that neutralise inclusion blennorrhoea virus. British Journal of Experimental Pathology 43:340–343
    [Google Scholar]
  6. Byrne G. I. 1978; Kinetics of phagocytosis of Chlamydia psittaci by mouse fibroblasts (L cells): separation of the attachment and ingestion stages. Infection and Immunity 19:607–612
    [Google Scholar]
  7. Byrne G. I., Moulder J. W. 1978; Parasite specified phagocytosis of Chlamydia psittaci and Chlamydia trachomatis by L and HeLa cells. Infection and Immunity 19:598–606
    [Google Scholar]
  8. Dulbecco R., Vogt M. 1954; Plaque formation and isolation of pure lines with poliomyelitis virus. Journal of Experimental Medicine 99:167–182
    [Google Scholar]
  9. Friis R. R. 1972; Interaction of L cells and Chlamydia psittaci: entry of the parasite and host responses to its development. Journal of Bacteriology 110:706–721
    [Google Scholar]
  10. Graham D. M., Layton J. E. 1971; The induction of chlamydia group antibody in rabbits inoculated with trachoma agents and demonstration of strain-specific neutralizing antibody in sera. In Trachoma and Related Disorders pp. 145–157 Nichols R. L. Edited by Amsterdam: Excerpta Medica;
    [Google Scholar]
  11. Griffiths M. S., Ainsworth S., Pearce J. H. 1976; Infectivity titration of guinea-pig inclusion conjunctivitis agent in irradiated McCoy cells. Journal of General Microbiology 95:249–256
    [Google Scholar]
  12. Howard L. V. 1975; Neutralisation of Chlamydia trachomatis in cell culture. Infection and Immunity 11:698–703
    [Google Scholar]
  13. Kuo C. C., Wang S. P., Grayston J. T. 1973; Effect of polycations, polyanions and neuramini-dase on the infectivity of trachoma-inclusion conjunctivitis and lymphogranuloma venereum organisms in HeLa cells: sialic acid residues as possible receptors for trachoma-inclusion con-junctivitis. Infection and Immunity 8:74–79
    [Google Scholar]
  14. Lawn A. M., Blyth W. A., Taverne J. 1973; Interactions of TRIC agents with macrophages and BHK-21 cells observed by electron microscopy. Journal of Hygiene, Cambridge 71:515–528
    [Google Scholar]
  15. Mogg A. E., Collier L. H., Harris R. G. 1971; The antibody response to primary and repeated intravenous injections of TRIC agent. In Trachoma and Related Disorders pp. 185–195 Nichols R. L. Edited by Amsterdam: Excerpta Medica;
    [Google Scholar]
  16. Moore J. E., Griffiths M. S., Pearce J. H. 1974; Chlamydial infection of conjunctival tissues in culture. British Journal of Experimental Pathology 55:396–405
    [Google Scholar]
  17. Nichols R. L., Oertley R. E., Fraser C. E.O., Macdonald A. B., McComb D. E. 1973; Immunity to chlamydial infections of the eye. VI. Homologous neutralisation of trachoma in- fectivity for the owl monkey conjunctivae by eye secretions from humans with trachoma. Journal of Infectious Diseases 127:429–432
    [Google Scholar]
  18. Pearce J. H, Ainsworth S., Allan I. 1978; Interaction of chlamydiae with host cell and mucous surfaces. Proceedings of the Society for General Microbiology 581–82
    [Google Scholar]
  19. Reeve P., Graham D. M. 1962; A neutralization test for trachoma and inclusion blennorrhoea viruses grown in HeLa cell cultures. Journal of General Microbiology 27:177–180
    [Google Scholar]
  20. Reeve P., Taverne J. 1962; A simple method for total particle counts of trachoma and inclusion blennorrhoea viruses. Nature London: 195923–924
    [Google Scholar]
  21. Sim I. S., Stephen J. 1975; Studies on the purification of chlamydial agents grown in yolk sacs of embryonated eggs using disulphide-linked immunosorbents and enzymes. Journal of General Microbiology 89:11–25
    [Google Scholar]
  22. Stirling P., Richmond S. 1977; The develop-mental cycle of Chlamydia trachomatis in McCoy cells treated with cytochalasin B. Journal of General Microbiology 100:31–42
    [Google Scholar]
  23. Wang S. P., Grayston J. T. 1971; Studies on the identity of the ‘fast’ egg-killing chlamydia strains. In Trachoma and Related Disorders pp. 322–336 Edited by Nichols R. L. Amsterdam: Excerpta Medica;
    [Google Scholar]
  24. Williams T. D., Hahon N. 1970; Serum neutralisation anti-IgG test for psittacosis. Infection and Immunity 2:7–10
    [Google Scholar]
  25. Zakay-Rones Z., Becker Y. 1971; Antibodies to trachoma elementary bodies. In Trachoma and Related Disorders pp. 254–259 Nichols R. L. Edited by Amsterdam: Excerpta Medica;
    [Google Scholar]
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