1887

Abstract

SUMMARY: The tripeptide L-methionyl-L-methionyl-L-[ C]methionine was taken up into by a saturable system with a pH optimum of 3.5, a temperature optimum of 37 C and an apparent of 3.3 × 10 M. Metabolic inhibitors such as sodium azide and dinitrophenol completely prevented uptake. Neither methionine nor dimethionine effectively competed with trimethionine uptake. (Leu) Gly-Met-Gly, acetyl-(Met) D-Met-L-Met-L-Met and Met-Met-Ile effectively competed with (Met) uptake, whereas (Lys) L-Met-L-Met-D-Met, D-Met-D-Met-D-Met, (Met) methyl ester and (Ala) did not. Trimethionine was rapidly hydrolysed by a peptidase after entry into the cell.

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/content/journal/micro/10.1099/00221287-114-1-179
1979-09-01
2020-01-23
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-114-1-179
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