1887

Abstract

Summary: The tripeptide -methionyl--methionyl--[ C]methionine was taken up into by a saturable system with a pH optimum of 3·5, a temperature optimum of 37 °C and an apparent of 33· 10 M. Metabolic inhibitors such as sodium azide and dinitrophenol completely prevented uptake. Neither methionine nor dimethionine effectively competed with trimethionine uptake. (Leu) Gly-Met-Gly, acetyl-(Met) D-Met--Met--Met and Met-Met-Ile effectively competed with (Met) uptake, whereas (Lys) -Met--Met--Met, -Met--Met--Met, (Met) methyl ester and (Ala) did not. Trimethionine was rapidly hydrolysed by a peptidase after entry into the cell.

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/content/journal/micro/10.1099/00221287-114-1-179
1979-09-01
2021-07-31
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