@article{mbs:/content/journal/micro/10.1099/00221287-113-2-377, author = "Shvinka, J. E. and Toma, M. K. and Galinina, N. I. and SkĀRds, I. V. and Viesturs, U. E.", title = "Production of Superoxide Radicals during Bacterial Respiration", journal= "Microbiology", year = "1979", volume = "113", number = "2", pages = "377-382", doi = "https://doi.org/10.1099/00221287-113-2-377", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-113-2-377", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "Summary: When sucrose or acetate was added to washed suspensions of a number of aerobic bacteria, exogenous ferricytochrome c 3+ was reduced, luminol chemiluminescence was enhanced and the rate of adrenaline auto-oxidation was increased. Superoxide dismutase from bovine erythrocytes inhibited all of there reactions, suggesting that superoxide radicals (O− 2) are formed during aerobic bacterial metabolism. Superoxide radicals were probably generated during respiratory chain activity because O− 2 production by intact bacteria was stimulated by antimycin A and the highest O− 2-producing activity was observed with membrane fractions with a high concentration of cytochromes. Exogenous superoxide dismutase partially inhibited NADH-dependent oxgyen consumption by membrane particles of Brevibacterium flavum 22LD.", }