@article{mbs:/content/journal/micro/10.1099/00221287-113-1-195, author = "Quain, D.E. and Haslam, J.M.", title = "Changes in Glucose 6-Phosphate and Storage Carbohydrates during Catabolite Derepression in Saccharomyces cerevisiae", journal= "Microbiology", year = "1979", volume = "113", number = "1", pages = "195-198", doi = "https://doi.org/10.1099/00221287-113-1-195", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-113-1-195", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "Changes in the cellular content of glucose 6-phosphate and storage carbohydrates during catabolite derepression were measured during the diauxic growth of Saccharomyces cerevisiae on glucose (1 %, w/v) medium. After the exhaustion of glucose there were transient increases in glucose 6-phosphate, alkali-soluble glycogen and trehalose, reflecting enhanced gluconeogenesis, followed by an increase in acid-soluble glycogen. During the subsequent adaptation to growth on ethanol the amounts of glucose 6-phosphate, trehalose and glycogen returned to basal levels. Thus storage carbohydrates, of which glycogen is quantitatively the most important, appear to act as the energy source for catabolite derepression.", }