RT Journal Article SR Electronic(1) A1 McConville, Malcolm L. A1 Charles, H. P.YR 1979 T1 Isolation of Haemin-requiring Mutants of Escherichia coli K12 JF Microbiology, VO 113 IS 1 SP 155 OP 164 DO https://doi.org/10.1099/00221287-113-1-155 PB Microbiology Society, SN 1465-2080, AB Fifty-five haemin-requiring mutants were isolated from haemin-permeable mutants. According to their growth responses to haem precursors and their patterns of porphyrin accumulation, the 55 mutants fell into three groups which were judged to have defects in 5-aminolaevulinate dehydratase, ferrochelatase, and uroporphyrinogen III cosynthase or uroporphyrinogen decarboxylase. In mutants of the group deficient in 5-aminolaevulinate dehydratase, the mutations were adjacent to lac, and evidence is presented that the mutations were in hem B and were commonly deletions extending into proC. , UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-113-1-155