1887

Abstract

dCyd deaminase and dUrd kinase did not appear to be important in the synthesis of dUTP in infected with phage PBS1. PBS1 infection did not affect the activities of dCyd kinase, dCyd deaminase, dCMP deaminase and ribonucleotide reductase. dUTP in PBS 1-infected cells was apparently formed by the action of dCTP deaminase induced by PBS 1, by host dCMP deaminase and by host UTP reductase. By labelling the phage DN A with radioactive precursors in hosts carrying various pyrimidine mutations, it was found that about 50 % of dUTP was derived from UTP reduction, 30 % from dCTP deamination and 20% from dCMP deamination.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-112-1-127
1979-05-01
2020-01-21
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-112-1-127
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error