1887

Abstract

dCyd deaminase and dUrd kinase did not appear to be important in the synthesis of dUTP in infected with phage PBS1. PBS1 infection did not affect the activities of dCyd kinase, dCyd deaminase, dCMP deaminase and ribonucleotide reductase. dUTP in PBS 1-infected cells was apparently formed by the action of dCTP deaminase induced by PBS 1, by host dCMP deaminase and by host UTP reductase. By labelling the phage DNA with radioactive precursors in hosts carrying various pyrimidine mutations, it was found that about 50% of dUTP was derived from UTP reduction, 30% from dCTP deamination and 20% from dCMP deamination.

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/content/journal/micro/10.1099/00221287-112-1-127
1979-05-01
2021-07-28
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