1887

Abstract

SUMMARY: A temperate phage of (), on addition to a non-Iysogenic indicator strain of the organism, produced a lysogenic culture with a high spontaneous rate of free phage production. A virulent mutant, serologically related to the temperate phage, was obtained from this lysogenic culture; this mutant did not give rise to lysogenically infected bacteria. Both virulent and temperate phages, acting on an indicator strain, had latent periods of 90 min., and the multiplication of each was inhibited by a phenanthridine added immediately after adsorption. This indicated that the initial stage of infection is the same for both types of phage. The production of free phage (i.e. the prophage to phage change) by the lysogenic culture derived from the temperate phage was not inhibited by the drug.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-11-1-105
1954-08-01
2021-08-03
Loading full text...

Full text loading...

/deliver/fulltext/micro/11/1/mic-11-1-105.html?itemId=/content/journal/micro/10.1099/00221287-11-1-105&mimeType=html&fmt=ahah

References

  1. Boyd J. S. K. 1951; Observations on the relationship of symbiotic and lytic bacteriophage. J. Path. Bact 63:445
    [Google Scholar]
  2. Dickinson L. 1948; The bacteriophages of Pseudomonas pyocyanea. 1. The effect of various substances upon their development. J. gen. Microbiol 2:154
    [Google Scholar]
  3. Dickinson L., Codd S. 1952; The bacteriophages of Pseudomonas pyocyanea. 2. Bacteriophage reproduction in an iridescent strain. J. gen. Microbiol 1:
    [Google Scholar]
  4. Gots J. S., Hunt G. R. 1953; Amino acid requirements for the maturation of bacteriophage in lysogenic Escherichia coli. J. Bact 66:353
    [Google Scholar]
  5. Jacob F., Lwoff A., Siminovitch A., Wollman E. 1953; Définition de quelques termes relatifs à la lysogénie. Ann. Inst. Pasteur 84:222
    [Google Scholar]
  6. Lieb M. 1953; The establishment of lysogenicity in Escherichia coli. J. Bact 65:643
    [Google Scholar]
  7. Lwoff A. 1953; Lysogeny. Bact. Rev 17:269
    [Google Scholar]
  8. Lwoff A., Gutmann A. 1950; Recherches sur un Bacillus megatherium lysogène. Ann. Inst. Pasteur 78:711
    [Google Scholar]
  9. Lwoff A., Siminovitch L., Kjeldgaard N. 1950; Induction de la production de bactériophage chez une bactérie lysogène. Ann. Inst. Pateur 79:815
    [Google Scholar]
  10. Miles R. F. N. 1953; The action of 2:7-bis(2′-dihydroglyoxalinyl)-9-phenyl-phenanthridine on a bacteriophage of Pseudomonas pyocyanea. Brit. J. Pharmacol 8:143
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-11-1-105
Loading
/content/journal/micro/10.1099/00221287-11-1-105
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error