Among 58 isoniazid-sensitive strains of Mycobacteriurn tuberculosis from India, Burma and East Africa, 23 were of phage type A, 31 of type T (intermediate), 4 of type B and none of type C. Type 1 strains differed from type A strains in being attenuated in the guinea-pig, susceptible to H 202, sensitive to thiophen-2-carboxylic acid hydrazide and resistant to thiacetazone and p-aminosalicylic acid; the content of strongly acidic lipids and of sul- phatide lipids was low and the attenuation indicator lipid was present. The pattern of results with the type B strains did not correspond to the patterns for types A or I. Strains of type I appear to be a distinct group within the species M. tuberculosis.


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