Protein Synthesis, Cell Division and the Cell Cycle in following a Shift to a Richer Medium Free

Abstract

When both haploid and diploid cells of the yeast were shifted to media supporting faster growth rates, rate maintenance of cell division was observed. Both protein synthesis and cell division displayed a variable period of rate maintenance prior to achieving new rates after shift-up; however, the interval between the increase in rate of protein synthesis and the increase in rate of cell division remained constant. These results are consistent with a model of the cell division cycle in which there is an expandable G1 phase during which growth to some critical size must be attained. Once cell division cycle events are initiated they proceed at a constant rate regardless of the overall population growth rate.

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/content/journal/micro/10.1099/00221287-106-2-221
1978-06-01
2024-03-28
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