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A simple method for studying the chemotactic responses of the plasmodium of Physarum polycephalum was designed. A positive chemotactic response was detected towards the sugars d-glucose, lactose, d-maltose and d-galactose, the amino acids l-leucine, l-serine and dl-phenylalanine, and the nucleotide uracil. The significance of chemotaxis in Physarum is discussed.
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