RT Journal Article SR Electronic(1) A1 Linstead, D. J. A1 Klein, R. A. A1 Cross, G. A. M.YR 1977 T1 Threonine Catabolism in Trypanosoma brucei JF Microbiology, VO 101 IS 2 SP 243 OP 251 DO https://doi.org/10.1099/00221287-101-2-243 PB Microbiology Society, SN 1465-2080, AB l-Threonine is catabolized by Trypanosoma brucei to give equimolar quantities of glycine and acetate. The pathway, which involves the two enzymes l-threonine dehydrogenase (EC 1.1.1.103) and aminoacetone synthase (acetyl-CoA: glycine C-acetyltransferase, EC 2.3.1.29) and subsequent hydrolysis of the acetyl-CoA, is most active in cultured trypanosomes but is also present in bloodstream forms. l-Threonine dehydrogenase from both culture and bloodstream forms of trypanosomes has an apparent molecular weight of between 28000 and 38000, and is sensitive to a wide range of sulphydryl reagents., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-101-2-243