1887

Abstract

SUMMARY: Particle counts of influenza virus preparations were made by two independent techniques; there was good agreement in the counts found by the two methods. Counts made on four strains of influenza virus and one strain of ‘incomplete’ virus showed that at the agglutination end-point there was about one virus particle per red cell. Parallel infectivity measurements of these strains made under optimal conditions showed that about ten virus particles corresponded to one ID 50.

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/content/journal/micro/10.1099/00221287-10-3-457
1954-06-01
2021-07-27
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References

  1. Cairns H. J. F., Fazekas de St Groth S., Edney M. 1952; Quantitative aspects of influenza virus multiplication. J. Immunol 69:155
    [Google Scholar]
  2. Dawson I. M., Elford W. J. 1949; The investigation of influenza and related viruses in the electron microscope, by a new technique. J. gen. Microbiol 3:298
    [Google Scholar]
  3. Fazekas de St Groth S. 1948; Modification of virus receptors by metaperiodate. I. The properties of IO4-treated red-cells. Aust. J. exp. Biol. med. Sci 27:65
    [Google Scholar]
  4. Fazekas de St Groth S., Cairns H. J. F. 1952; Quantitative aspects of influenza virus multiplication. IV. Definition of constants and general discussion. J. Immunol 69:173
    [Google Scholar]
  5. Friedewald W. F., Pickets E. G. 1944; Centrifugation and ultrafiltration studies on allantoic fluid preparations of influenza virus. J. exp. Med 79:301
    [Google Scholar]
  6. Fulton F., Armitage P. 1951; Surviving tissue suspensions for influenza virus titration. J. Hyg., Camb 49:247
    [Google Scholar]
  7. Henle W. 1950; Interference phenomena between animal viruses: a review. J. Immunol 64:203
    [Google Scholar]
  8. Henle W., Henle G., Rosenberg E. B. 1947; The demonstration of one-step growth curves of influenza viruses through the blocking effect of irradiated virus on further infection. J.exp. Med 86:423
    [Google Scholar]
  9. Liu O. C., Henle W. 1953; Studies on host-virus interactions in the chick embryo-influenza virus system. VII. Data concerning the significance of infectivity titration end-points and the separation of clones at limiting dilutions. J. exp. Med 97:889
    [Google Scholar]
  10. Luria S. E. 1953 General Virology New York: John Wiley & Sons Inc;
    [Google Scholar]
  11. Luria S. E., Williams R. C., Backus R. C. 1951; Electron micrographic counts of bacteriophage particles. J. Bact 61:179
    [Google Scholar]
  12. Magnus P. von. 1946; Studies on interference in experimental influenza. I. Biological observations. Arkiv. Kemi Min. Geol 24 B:1
    [Google Scholar]
  13. Magnus P. von. 1951; Propagation of the PR8 strain of influenza A virus in chick embryos. II. The formation of ‘incomplete’ virus following inoculation of large doses of seed virus. Acta path, microbiol. scand 28:278
    [Google Scholar]
  14. Reed L. J., Muench H. 1938; A simple method of estimating fifty per cent endpoints. Amer. J. Hyg 27:493
    [Google Scholar]
  15. Smadel J. E., Rivers T. M., Pickels E. G. 1939; Estimation of the purity of preparations of elementary bodies of vaccinia. J. exp. Med 70:379
    [Google Scholar]
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