The Production of Free Staphylococcal Coaǵulase Free

Abstract

Free staphylococcal coagulase is formed early in the lag phase and is released continuously, mainly at the first division in heavily seeded cultures. With most strains the presence of serum albumin in the medium greatly enhances the production of both free and bound coagulase (Duthie, 1954). The albumin factor is relatively heat stable, but is easily destroyed by crystalline trypsin.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-10-3-437
1954-06-01
2024-03-28
Loading full text...

Full text loading...

/deliver/fulltext/micro/10/3/mic-10-3-437.html?itemId=/content/journal/micro/10.1099/00221287-10-3-437&mimeType=html&fmt=ahah

References

  1. Biggs R., Macfarlane R. G. 1953 Human Blood Coagulation and its Disorders Oxford: Blackwell Scientific Publications;
    [Google Scholar]
  2. Davies G. E. 1951; Factors influencing the in vitro production of staphylococcal coagulase. J. gen. Microbiol 5:687
    [Google Scholar]
  3. Duthie E. S. 1952; Variation in the antigenic composition of staphylococcal coagulase. J. gen. Microbiol 7:320
    [Google Scholar]
  4. Duthie E. S. 1954; Evidence for two forms of staphylococcal coagulase. J. gen. Microbiol 10:427
    [Google Scholar]
  5. Duthie E. S., Lorenz L. 1949; Protease inhibitors. 2. Bacterial proteases and their inhibitors. Biochem. J 44:173
    [Google Scholar]
  6. Duthie E. S., Lorenz L. 1952; Staphylococcal coagulase; mode of action and antigenicity. J. gen. Microbiol 6:95
    [Google Scholar]
  7. Lominski I. 1944; Preparations of cell-free plasma coagulase of Staphylococcus aureus. Nature; Land: 154640
    [Google Scholar]
  8. Lominski I., Smith D. D., Morrison R. B. 1953; A coagulase-destroying factor produced by variants of Staphylococcus aureus. Nature; Lond: 171214
    [Google Scholar]
  9. Miale J. B. 1949; The role of staphylocoagulase in blood coagulation. I. The reaction of staphylocoagulase with coagulase globulin (CG) to form coagulase thrombin (CT). Blood 4:1039
    [Google Scholar]
  10. Tager M., Hales H. B. 1947; Qualitative coagulase and toxin production by staphylococci in relation to the clinical source of the organisms. Yale J. Biol. Med 20:41
    [Google Scholar]
  11. Walker B. S., Derow M. A., Schaffer N. K. 1948; The partial purification of staphylocoagulase and the effects of certain presumptive inhibitors upon its plasma-coagulating action. J. Bact 56:191
    [Google Scholar]
  12. Walston H. D. 1935; The clotting of plasma through staphylococci and their products. J. Hyg., Camb 35:549
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-10-3-437
Loading
/content/journal/micro/10.1099/00221287-10-3-437
Loading

Data & Media loading...

Most cited Most Cited RSS feed