%0 Journal Article %A Duthie, E. S. %T The Production of Free Staphylococcal Coaǵulase %D 1954 %J Microbiology, %V 10 %N 3 %P 437-444 %@ 1465-2080 %R https://doi.org/10.1099/00221287-10-3-437 %I Microbiology Society, %X Free staphylococcal coagulase is formed early in the lag phase and is released continuously, mainly at the first division in heavily seeded cultures. With most strains the presence of serum albumin in the medium greatly enhances the production of both free and bound coagulase (Duthie, 1954). The albumin factor is relatively heat stable, but is easily destroyed by crystalline trypsin. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-10-3-437