1887

Abstract

SUMMARY: Spermine was found to inhibit the growth of various micro-organisms. The most susceptible were and and , and to a lesser degree . The Enterobacteriaceae were relatively resistant. The action of spermine was enhanced by an increase in pH of the medium. The antibacterial effect was bactericidal; it was slowed but not prevented by a decrease in temperature from 37 to 6°. The nutrients of various media influenced the action of spermine.

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/content/journal/micro/10.1099/00221287-10-1-11
1954-02-01
2024-04-25
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References

  1. Bichowsky-slomnitzki L. 1948; The effect of aromatic diamidines on bacterial growth. J. Bact. 55:27
    [Google Scholar]
  2. Guggenheim M. 1940 Die biogenenAmine, 3rd edition,. p. 229 Basel, New York:: S. Karger;
    [Google Scholar]
  3. Gurevitch J., Rozansky R., Weber D., Brzezinsky A., Eckerling B. 1951; Role of spermine in the inhibition of Staphylococcus aureus by human semen. J. clin. Path. 4:360
    [Google Scholar]
  4. Harrison G.A. 1933; The approximate determination of spermine in single human organs. Biochem. J. 27:1152
    [Google Scholar]
  5. Herbst E.J., Snell E.E. 1948; Putrescine as a growth factor for Hemophilusparainfluenzae. J. biol. Chem. 176:989
    [Google Scholar]
  6. Hirsch J.G., Dubos R.J. 1952; The effect of spermine on tubercle bacilli. J. exp. Med. 95:191
    [Google Scholar]
  7. Miller A.K., Peters L. 1945; The antagonism by spermine and spermidine of the antibacterial action of quinacrine and other drugs. Arch. Biochem. 6:281
    [Google Scholar]
  8. Rozansky R., Gurevitch J., Brzezinsky A., Eckerling B. 1949; Inhibition of the growth ofStaphylococcus aureusby human semen. J. lab. clin. Med. 34:1526
    [Google Scholar]
  9. Silverman M., Evans .E.A. Jun. 1943; The effects of spermidine and other polyamines on growth inhibition ofEscherichia coliby atabrine. J. biol. Chem. 150:263
    [Google Scholar]
  10. Silverman M., Evans E.A. Jun. 1944; Effect of spermine, spermidine and other polyamines on growth inhibition ofEscherichia coliby atabrine. J. biol. Chem. 154:521
    [Google Scholar]
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