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Volume 11, Issue 2

The complete genome sequence of nudivirus (previously Baculovirus penaei or singly enveloped nuclear polyhedrosis virus) Open Access

Abstract

singly enveloped nuclear polyhedrosis virus (PvSNPV), also known as Baculovirus penaei (BP), is the first viral pathogen of penaeid shrimp described in 1974. Although PvSNPV was discovered almost 50 years ago, the complete genome sequence has not been elucidated until now. We detected the virus in a quarantine stock of shrimp by light microscopy of faecal samples and by PCR screening of broodstock. Subsequently, next-generation sequencing was deployed to determine the complete genome sequence of PvSNPV. The PvSNPV genome is a circular, double-stranded DNA molecule of 119 883 bp in length encoding 101 ORFs. The deduced sequences from 28 ORFs were homologous to 28 core proteins from all identified nudiviruses. Phylogenetic analyses based on deduced sequences of the core genes and orthologous genes revealed that PvSNPV clusters with nudivirus. Therefore, we propose to rename BP/PvSNPV as nudivirus and re-assign the virus to the family instead of .

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): BP , nudivirus , Penaeus vannamei and PvSNPV
Funding
This study was supported by the:
  • Aquaculture Pathology Laboratory, The University of Arizona
    • Principal Award Recipient: ArunK. Dhar
© 2025 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
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2026-04-15

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The complete genome sequence of Penaeus vannamei nudivirus (previously Baculovirus penaei or P. vannamei singly enveloped nuclear polyhedrosis virus)
M Gen 11, 001360 (2025); https://doi.org/10.1099/mgen.0.001360
/content/journal/mgen/10.1099/mgen.0.001360
/content/journal/mgen/10.1099/mgen.0.001360
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