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Volume 9, Issue 7

from grass: novel but non-resistant clones Open Access

Abstract

is one the most worrisome nosocomial pathogens, which has long been considered almost mainly as a hospital-associated bacterium. There have been some studies about animal and environmental isolates over the last decade. However, little effort has been made to determine if this pathogen dwells in the grass. Here, we aim to determine the evolutionary relationships and antibiotic resistance of clones of sampled from grass to the major human international clones and animal clones. Two hundred and forty genomes were considered in total from four different sources for this study. Our core and accessory genomic epidemiology analyses showed that grass isolates cluster in seven groups well differentiated from one another and from the major human and animal isolates. Furthermore, we found new sequence types under both multilocus sequence typing schemes: two under the Pasteur scheme and seven for the Oxford scheme. The grass isolates contained fewer antibiotic-resistance genes and were not resistant to the antibiotics tested. Our results demonstrate that these novel clones appear to have limited antibiotic resistance potential. Given our findings, we propose that genomic epidemiology and surveillance of should go beyond the hospital settings and consider the environment in an explicit One Health approach.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): Acinetobacter baumannii , antibiotic resistance , Genomic epidemiology , grass , international clones , non-clinical environments and One Health
Funding
This study was supported by the:
  • CONACyT PhD fellowship (Award 1005234)
    • Principle Award Recipient: ValeriaMateo-Estrada
  • CONACyT Ciencia Básica (Award 284276)
    • Principle Award Recipient: SantiagoCastillo-Ramirez
  • Programa de Apoyo a Proyectos de Investigación e Innovación Tecnológica PAPIIT (Award IN206019)
    • Principle Award Recipient: SantiagoCastillo-Ramirez
  • Walsh Fellowship (Award 2017037)
    • Principle Award Recipient: TyrrellCiara
© 2023 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
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2023-07-13
2024-12-06
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/content/journal/mgen/10.1099/mgen.0.001054
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Acinetobacter baumannii from grass: novel but non-resistant clones
M Gen 9, 001054 (2023); https://doi.org/10.1099/mgen.0.001054
/content/journal/mgen/10.1099/mgen.0.001054
/content/journal/mgen/10.1099/mgen.0.001054
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