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Volume 9, Issue 3

Substantial viral and bacterial diversity at the bat–tick interface Open Access

Abstract

Ticks harbour a high diversity of viruses, bacteria and protozoa. The soft tick (Argasidae) is a common ectoparasite of bats in the Palearctic region and is suspected to be vector and reservoir of viruses and other microbial species in bat populations, some of which may act as zoonotic agents for human disease. The Soprano pipistrelle (, Vespertilionidae) is widely distributed in Europe, where it can be found inside or close to human habitation. We used meta-transcriptomic sequencing to determine the RNA virome and common microbiota in blood-fed ticks collected from a Soprano pipistrelle bat roosting site in south-central Sweden. Our analyses identified 16 viruses from 11 virus families, of which 15 viruses were novel. For the first time in Sweden we identified Issuk-Kul virus, a zoonotic arthropod-borne virus previously associated with outbreaks of acute febrile illness in humans. Probable bat-associated and tick-borne viruses were classified within the families and , while other invertebrate-associated viruses included members of the , , , , and . Similarly, we found abundant bacteria in including genera with known tick-borne bacteria, such as spp. and spp. These findings demonstrate the remarkable diversity of RNA viruses and bacteria present in and highlight the importance of bat-associated ectoparasite surveillance as an effective and non-invasive means to track viruses and bacteria circulating in bats and ticks.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): Carios vespertilionis , meta-transcriptomics , Pipistrellus pygmaeus , RNA virome and virus evolution
Funding
This study was supported by the:
  • Forskningsrådet i Sydöstra Sverige (Award FORSS, 931010)
    • Principle Award Recipient: PeterWilhelmsson
  • Innovation and Technology Commission (Award AIR@InnoHK)
    • Principle Award Recipient: EdwardC Holmes
  • Australian Research Council (Award FL170100022)
    • Principle Award Recipient: EdwardC Holmes
  • Vetenskapsrådet (Award 2020-02593)
    • Principle Award Recipient: JohnPettersson
  • Svenska Forskningsrådet Formas (Award 2015-710)
    • Principle Award Recipient: JohnPettersson
© 2023 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
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Substantial viral and bacterial diversity at the bat–tick interface
M Gen 9, 000942 (2023); https://doi.org/10.1099/mgen.0.000942
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