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Volume 5, Issue 7

Genomics of vancomycin-resistant Open Access

Abstract

Vancomycin-resistant (VREfm) is a globally significant public health threat and was listed on the World Health Organization’s 2017 list of high-priority pathogens for which new treatments are urgently needed. Treatment options for invasive VREfm infections are very limited, and outcomes are often poor. Whole-genome sequencing is providing important new insights into VREfm evolution, drug resistance and hospital adaptation, and is increasingly being used to track VREfm transmission within hospitals to detect outbreaks and inform infection control practices. This mini-review provides an overview of recent data on the use of genomics to understand and respond to the global problem of VREfm.

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  • Accepted:
  • Published Online:
Keyword(s): antibiotic resistance , Enterococcus faecium and whole-genome sequencing
© 2019 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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2019-07-22
2024-04-20
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Genomics of vancomycin-resistant Enterococcus faecium
M Gen 5, e000283 (2019); https://doi.org/10.1099/mgen.0.000283
/content/journal/mgen/10.1099/mgen.0.000283
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