- Volume 2, Issue 1, 2015
Volume 2, Issue 1, 2015
- Case Review
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- Respiratory
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Extrapulmonary intrathoracic blastomycosis: a case report and systematic literature review
More LessIntroduction:Mediastinal blastomycosis has been described in multiple case reports, but no review to date has catalogued its various manifestations or response to treatment.
Case presentation:An otherwise healthy 18‐year‐old female presented with lymphadenopathy and was found to have a large mediastinal mass concerning for lymphoma. A subsequent biopsy revealed Blastomyces dermatitidis; the patient responded well to therapy with amphotericin B and itraconazole. Similar cases are reviewed and analysed.
Conclusion:Mediastinal blastomycosis is a rare but life‐threatening disease manifestation that responds readily to appropriate antifungal therapy.
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