1887

Abstract

Introduction:

is an uncommon pathogen rarely associated with clinical infections. Previous studies showed that most isolates were sensitive to cephalosporins, aminoglycosides, fluoroquinolones and carbapenems, and no extensively drug‐resistant (XDR) strains have been reported.

Case presentation:

In this study, an XDR strain, RP01, was isolated from a Chinese patient with multiple chronic diseases. Antimicrobial susceptibility testing showed that RP01 was resistant to almost all clinically available antibiotics except tigecycline. PCR and sequencing revealed the presence of , encoding a metallo‐‐lactamase with hydrolysing activity against carbapenems. Further genomic sequencing and ResFinder analysis identified 20 resistance genes, encoding resistance to ‐lactams, aminoglycosides, sulfonamides, tetracycline, fluoroquinolones, trimethoprim and fosfomycin.

Conclusion:

These results described the ability of the rare pathogen to acquire multiple resistance genes.

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2014-09-01
2019-10-23
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