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Abstract

Introduction:

Mediterranean spotted fever (MSF) is a tick-borne acute febrile disease caused by . Most cases follow a benign course, with a case fatality rate of 3–7 % among hospitalized patients. Complications are described mainly in adult patients and include hepatic, renal, neurological and cardiac impairment. Among cardiac complications, pericarditis, myocarditis and heart rhythm disorders are uncommon complications in MSF and only a few cases have been reported in the literature.

Case Presentation:

We describe a new case of acute myocarditis complicating MSF in an immunocompetent adult patient without risk factors for severe MSF.

Conclusion:

Myocarditis is an uncommon but severe complication of MSF. Clinicians should be aware of a possible cardiac involvement in patients with MSF. Close monitoring and an aggressive approach are essential to reduce mortality rates of MSF.

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2016-07-11
2024-12-08
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References

  1. Bellini C., Monti M., Potin M., Ave A. D., Bille J., Greub G. 2005; Cardiac involvement in a patient with clinical and serological evidence of African tick-bite fever. BMC Infect Dis 5:90 [View Article][PubMed]
    [Google Scholar]
  2. Ben Mansour N., Barakett N., Hajlaoui N., Haggui T., Filali T., Dahmen R., Fehri W., Haouala H. 2014; Acute myocarditis complicating Mediterranean spotted fever. A case report. Ann Cardiol Angeiol 63:55–57 [CrossRef]
    [Google Scholar]
  3. Bradford W. D., Hackel D. B. 1978; Myocardial involvement in Rocky Mountain spotted fever. Arch Pathol Lab Med 102:357–359[PubMed]
    [Google Scholar]
  4. Cascio A., Colomba C., Antinori S., Paterson D. L., Titone L. 2001; Clarithromycin versus azithromycin in the treatment of mediterranean spotted fever in children: a randomized controlled trial. Clin Infect Dis 33:409–411 [View Article][PubMed]
    [Google Scholar]
  5. Cascio A., Colomba C., Antinori S., Paterson D. L., Titone L. 2002; Clarithromycin versus azithromycin in the treatment of Mediterranean spotted fever in children: a randomized controlled trial. Clin Infect Dis 34:154–158 [View Article][PubMed]
    [Google Scholar]
  6. Cascio A., Maggio M. C., Cardella F., Zangara V., Accomando S., Costa A., Iaria C., Mansueto P., Giordano S. 2011; Coronary involvement in Mediterranean spotted fever. New Microbiol 34:421–424[PubMed]
    [Google Scholar]
  7. Colomba C., Saporito L., Polara V. F., Rubino R., Titone L. 2006; Mediterranean spotted fever: clinical and laboratory characteristics of 415 Sicilian children. BMC Infect Dis 60:
    [Google Scholar]
  8. Colomba C., Saporito L., Colletti P., Mazzola G., Rubino R., Pampinella D., Titone L. 2008; Atrial fibrillation in Mediterranean spotted fever. J Med Microbiol 57:1424–1426 [View Article][PubMed]
    [Google Scholar]
  9. Colomba C., Imburgia C., Trizzino M., Titone L. 2014; First case of Mediterranean spotted fever-associated rhabdomyolysis leading to fatal acute renal failure and encephalitis. Int J Infect Dis 26:12–13 [CrossRef]
    [Google Scholar]
  10. de Groot R., Oranje A. P., van der Heyden A. J., Vuzevski V. D., Schaap G. J., van Joost T. 1984; Rickettsia conorii infection complicated by supraventricular tachycardia in a ten year-old child. Acta Leiden 52:45–52[PubMed]
    [Google Scholar]
  11. Duque V., Ventura C., Seixas D., Barai A., Mendonca N., Martins J., da Cunha S., Melico-Silvestre A. 2012; Mediterranean spotted fever and encephalitis: a case report and review of the literature. J Infect Chemother 18:105–108 [CrossRef]
    [Google Scholar]
  12. Fukuta Y., Mahara F., Nakatsu T., Yoshida T., Nishimura M. 2007; A case of Japanese spotted fever complicated with acute myocarditis. Jpn J Infect Dis 60:59–61
    [Google Scholar]
  13. Grand A., Guillermet F. N., Despret P., Kreuter M., Hintzy L. 1975; Acute pericarditis caused by Rickettsia conori . Arch Mal Coeur Vaiss 68:1225–1231[PubMed]
    [Google Scholar]
  14. Lisa Catón V., Ochoa Gómez F. J., Peña Somovilla J. L., Salcedo Aguilar J., Ruiz Valverde A., Campo Hernández J. M. 1991; Myocarditis caused by Mediterranean boutonneuse fever. Enferm 9:59
    [Google Scholar]
  15. Lunge S. B., Patil V., Ambar S., Naik V. 2015; Malignant Mediterranean spotted fever. Indian Dermatol Online J 6:s1–4 [View Article][PubMed]
    [Google Scholar]
  16. Marcon G., Callegari E., Scevola M., Bettin M., Pozzati G., Zolli M., Carlassara G. B. 1988; Acute rickettsial myocarditis. Description of a clinical case and review of the literature. G Ital Cardiol 18:72–75[PubMed]
    [Google Scholar]
  17. Mekhloufi E. Y., Ait-Abbas N. 2001; [Mediterranean spotted fever complicated by myocarditis. Presse Med 30:586[PubMed]
    [Google Scholar]
  18. Nilsson K., Liu A., Påhlson C., Lindquist O. 2005; Demonstration of intracellular microorganisms (Rickettsia spp., Chlamydia pneumoniae, Bartonella spp.) in pathological human aortic valves by PCR. J Infect 50:46–52 [View Article][PubMed]
    [Google Scholar]
  19. Patil H., Shahapur P., Bidari L. H. 2010; Myocarditis and Rickettsia conorii infection. PediatricOncall [serial online].
  20. Salvi A., Della Grazia E., Silvestri F., Camerini F. 1985; Acute rickettsial myocarditis and advanced atrioventricular block: diagnosis and treatment aided by endomyocardial biopsy. Int J Cardiol 7:405–409[PubMed] [CrossRef]
    [Google Scholar]
  21. Saporito L., Giammanco G. M., Rubino R., Ingrassia D., Spicola D., Titone L., Colomba C. 2010; Severe Mediterranean spotted fever complicated by acute renal failure and herpetic oesophagitis. J Med Microbiol 59:990–992 [View Article][PubMed]
    [Google Scholar]
  22. Scaffidi A., Furitano G., Scaffidi L. 1981; Cardiovascular involvement and complications in Mediterranean boutonneuse fever. Minerva Med 72:2097–2108[PubMed]
    [Google Scholar]
  23. Sittiwangkul R., Pongprot Y., Silviliarat S., Oberdorfer P., Jittamala P., Sirisanthana V. 2008; Acute fulminant myocarditis in scrub typhus. Ann Trop Paediatr 28:149–154 [View Article][PubMed]
    [Google Scholar]
  24. Walker D. H., Paletta C. E., Cain B. G. 1980; Pathogenesis of myocarditis in Rocky Mountain spotted fever. Arch Pathol Lab Med 104:171–174[PubMed]
    [Google Scholar]
  25. Yancy C. W., Jessup M., Bozkurt B., Butler J., Casey D. E., Drazner M. H., Fonarow G. C., Geraci S. A., Horwich T. et al. 2013; ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 62:e147239 [View Article][PubMed]
    [Google Scholar]
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