RT Journal Article SR Electronic(1) A1 Biron, Antoine A1 Cazorla, Cécile A1 Amar, Julien A1 Pfannstiel, Anne A1 Dupont-Rouzeyrol, Myrielle A1 Goarant, CyrilleYR 2016 T1 Zika virus infection as an unexpected finding in a Leptospirosis patient JF JMM Case Reports, VO 3 IS 3 OP SP e005033 DO https://doi.org/10.1099/jmmcr.0.005033 PB Microbiology Society, SN 2053-3721, AB Introduction: Areas where leptospirosis and arboviruses are endemic largely overlap in the tropics. However, the number of arbovirus infections is usually much higher. The initial clinical presentation can be highly confusing; therefore, laboratory confirmation is key to an accurate diagnosis. Case Presentation: A 19–year–old man presented to a peripheral health centre with an acute febrile illness. Dengue was initially suspected, but the patient deteriorated to a shock syndrome. Leptospirosis as well as a co-infection with Zika virus were both confirmed in the laboratory, the latter being clinically masked in this dual infection. Conclusion: This case highlights the importance of not only considering the differential diagnosis of acute febrile syndromes, but also to consider the possibility of dual infections in the context of global spread of arboviruses. The specific context of travellers returning from endemic areas and pregnant women is also highlighted and discussed. , UL https://www.microbiologyresearch.org/content/journal/jmmcr/10.1099/jmmcr.0.005033