1887

Abstract

Introduction:

The family is divided into several genera, including the genus , which includes the species to - and to −. These viruses are frequently associated with respiratory and gastrointestinal diseases. Coxsackie virus and echoviruses can induce a rash in children, such as hand-foot-and-mouth disease caused by coxsackie virus A16, while rhinoviruses are associated mainly with respiratory infections.

Case presentation:

We describe a clinical case of mild rhinitis in a 9-week-old female infant with HBoV and enterovirus co-infection accompanied by an unusual rash that strongly resembled granuloma annulare, having plaques with raised non-scaly erythematous borders. The child was afebrile, displayed a garland-like rash that within minutes changed its pattern and had moderately elevated expression of tryptase. No other pathogens were detected.

Conclusion:

It was concluded that the rash originated from the double infection with enterovirus and HBoV, as no further rash-associated pathogens were detected. The case is important as it is the first description, to the best of our knowledge, of this unusual rash seen with enterovirus/HBoV co-infection, and as this condition should be taken into account in future.

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/content/journal/jmmcr/10.1099/jmmcr.0.005012
2015-12-13
2020-01-19
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