1887

Abstract

Introduction:

Neonatal mastitis is an inflammatory condition of the breast frequently associated with While Panton–Valentine leucocidin (PVL), a B‐pore‐forming cytotoxin, is commonly associated with enhanced virulence in community‐acquired methicillin‐resistant isolates, this is the first report to our knowledge of neonatal mastitis caused by PVL‐positive .

Case presentation:

A 20‐day‐old full‐term female neonate presented with bilateral mastitis, complicated by bilateral abscess formation. PVL toxin‐positive was cultured from aspirates of both breasts. All family members, none of whom presented with symptoms of infection, and, specifically, maternal vaginal samples proved negative for PVL‐positive . Successful resolution involved surgical drainage and clindamycin therapy.

Conclusion:

While PVL toxin‐positive has previously been implicated in bovine and ovine mastitis, there may now be a need for vigilance with respect to human incidence. Due to PVL‐mediated tissue necrosis, breast abscess formation and poor response to conventional antimicrobial therapy should, perhaps, be a cause for suspicion of PVL‐bearing and expediting of appropriate therapy to avoid potential for long‐term consequences such as abnormal breast development.

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2014-09-01
2019-10-21
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