1887

Abstract

Introduction:

Melanized or dematiaceous fungi are associated with a wide variety of infectious syndromes. is one of the most common and dangerous neurotropic fungi, able to cause brain abscess and disseminated infection.

Case Presentation:

We report a new case of phaeohyphomycosis brain abscesses caused by in Slovakia. The patient was a 63‐year‐old man having undergone heart transplantation, with dyspnoea, left‐sided bronchopneumonia and fevers. CT (computed tomography) and MRI (magnetic resonance imaging) of the brain revealed numerous abscesses. Bacterial infection was proven by neither the growth of bacteria in culture nor the presence of bacterial antigens. Direct microscopy of the pus from the brain abscess showed Gram‐positive hyphae. The isolate was finally identified as based on morphological and physiological features, and on DNA sequence analysis.

Conclusion:

In spite of appropriate therapy, neurological complications and accelerated respiratory insufficiency resulted in the patient’s death. Concerning clinical manifestation of the brain phaeohyphomycosis that can sometimes be a problem to distinguish from malignancy, physicians should also assume infection caused by this serious pathogen.

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2014-12-01
2019-10-20
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