1887

Abstract

Introduction:

We describe an unusual case of anaerobic bacteraemia caused by and , both commensal organisms normally found within human oropharyngeal, gastrointestinal and genitourinary tracts.

Case presentation:

One week following a routine colonoscopy with polypectomy, a 65‐year‐old male with renal calculi was admitted with a 3‐day history of severe abdominal pain and chills. He required urgent placement of a percutaneous nephrostomy tube. Urine cultures were negative but blood cultures were positive for and .

Conclusions:

We hypothesized that, following his colonoscopy, the patient developed transient bacteraemia with commensal gut organisms. In the setting of multiple ureteral calculi, this transient bacteraemia became a clinically significant infection, manifesting as acute ureterolithiasis with concurrent bloodstream infection. The routine collection of blood for anaerobic culture led to pathogen identification and appropriate antimicrobial therapy.

  • This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/).
Loading

Article metrics loading...

/content/journal/jmmcr/10.1099/jmmcr.0.002139
2014-09-01
2024-12-05
Loading full text...

Full text loading...

/deliver/fulltext/jmmcr/1/3/jmmcr002139.html?itemId=/content/journal/jmmcr/10.1099/jmmcr.0.002139&mimeType=html&fmt=ahah

References

  1. Afra K., Laupland K., Leal J., Lloyd T., Gregson D. ( 2013). Incidence, risk factors, and outcomes of Fusobacterium species bacteremia. BMC Infect Dis 13:264 [CrossRef]
    [Google Scholar]
  2. Bannon J., Hatem M.H., Noone M. ( 1998). Anaerobic infections of the urinary tract: are they being missed?. J Clin Pathol 51:709–710 [CrossRef]
    [Google Scholar]
  3. Bennett K.W., Eley A. ( 1993). Fusobacteria: new taxonomy and related diseases. J Med Microbiol 39:246–254 [CrossRef]
    [Google Scholar]
  4. Bourgault A.M., Lamothe F., Dolcé P., Saint‐Jean L., Saint‐Antoine P. ( 1997). Fusobacterium bacteremia: clinical experience with 40 cases. Clin Infect Dis Off Publ Infect Dis Soc Am 25:Suppl. 2S181–S183 [CrossRef]
    [Google Scholar]
  5. Brazier J.S., Hall V., Yusuf E., Duerden B.I. ( 2002). Fusobacterium necrophorum infections in England and Wales 1990–2000. J Med Microbiol 51:269–272
    [Google Scholar]
  6. Brook I. ( 1988). Recovery of anaerobic bacteria from clinical specimens in 12 years at two military hospitals. J Clin Microbiol 26:1181–1188
    [Google Scholar]
  7. Brook I. ( 1994). Fusobacterial infections in children. J Infect 28:155–165 [CrossRef]
    [Google Scholar]
  8. Candoni A., Filì C., Trevisan R., Silvestri F., Fanin R. ( 2003). Fusobacterium nucleatum: a rare cause of bacteremia in neutropenic patients with leukemia and lymphoma. Clin Microbiol Infect Off Publ Eur Soc Clin Microbiol Infect Dis 9:1112–1115
    [Google Scholar]
  9. Chun Y.J., Yoon N.R., Park J.M., Lim C‐H., Cho Y.K., Lee I.S., Kim S.W., Choi M‐G., Choi K.Y., Chung I‐S. ( 2012). Prospective assessment of risk of bacteremia following colorectal stent placement. Dig Dis Sci 57:1045–1049 [CrossRef]
    [Google Scholar]
  10. Epaulard O., Brion J‐P., Stahl J‐P., Colombe B., Maurin M. ( 2006). The changing pattern of Fusobacterium infections in humans: recent experience with Fusobacterium bacteraemia. Clin Microbiol Infect 12:178–181 [CrossRef]
    [Google Scholar]
  11. George W.L., Kirby B.D., Sutter V.L., Citron D.M., Finegold S.M. ( 1981). Gram‐negative anaerobic bacilli: their role in infection and patterns of susceptibility to antimicrobial agents. II. Little‐known Fusobacterium species and miscellaneous genera. Rev Infect Dis 3:599–626 [CrossRef]
    [Google Scholar]
  12. Gillis K., Seenan J.P., Cahill A., Tyers A., Khanna N., Edwards G.F.S., Diggle M.A. ( 2011). An unusual infection in an injecting drug user. Scott Med J 56:59 [CrossRef]
    [Google Scholar]
  13. Goldberg E.A., Venkat‐Ramani T., Hewit M., Bonilla H.F. ( 2012). Epidemiology and clinical outcomes of patients with Fusobacterium bacteraemia. Epidemiol Infect1–5
    [Google Scholar]
  14. Hartong W.A., Barnes W.G., Calkins W.G. ( 1977). The absence of bacteremia during colonoscopy. Am J Gastroenterol 67:240–244
    [Google Scholar]
  15. Kumar S., Abcarian H., Prasad M.L., Lakshmanan S. ( 1982). Bacteremia associated with lower gastrointestinal endoscopy, fact or fiction? I. Colonoscopy. Dis Colon Rectum 25:131–134 [CrossRef]
    [Google Scholar]
  16. Kumar S., Abcarian H., Prasad M.L., Lakshmanan S. ( 1983). Bacteremia associated with lower gastrointestinal endoscopy: fact or fiction? II. Proctosigmoidoscopy. Dis Colon Rectum 26:22–24 [CrossRef]
    [Google Scholar]
  17. Kunz A.N., Riera D., Hickey P. ( 2009). Case of Clostridium perfringens bacteremia after routine colonoscopy and polypectomy. Anaerobe 15:195–196 [CrossRef]
    [Google Scholar]
  18. Low D.E., Shoenut J.P., Kennedy J.K., Sharma G.P., Harding G.K., Den Boer B., Micflikier A.B. ( 1987). Prospective assessment of risk of bacteremia with colonoscopy and polypectomy. Dig Dis Sci 32:1239–1243 [CrossRef]
    [Google Scholar]
  19. Min B‐H., Chang D.K., Kim D.U., Kim Y‐H., Rhee P‐L., Kim J.J., Rhee J.C. ( 2008). Low frequency of bacteremia after an endoscopic resection for large colorectal tumors in spite of extensive submucosal exposure. Gastrointest Endosc 68:105–110 [CrossRef]
    [Google Scholar]
  20. Minces L.R., Shields R.K., Sheridan K., Ho K.S., Silveira F.P. ( 2010). Peptostreptococcus infective endocarditis and bacteremia. Analysis of cases at a tertiary medical center and review of the literature. Anaerobe 16:327–330 [CrossRef]
    [Google Scholar]
  21. Ngo J.T., Parkins M.D., Gregson D.B., Pitout J.D.D., Ross T., Church D.L., Laupland K.B. ( 2013). Population‐based assessment of the incidence, risk factors, and outcomes of anaerobic bloodstream infections. Infection 41:41–48 [CrossRef]
    [Google Scholar]
  22. Nohrström E., Mattila T., Pettilä V., Kuusela P., Carlson P., Kentala E., Mattila P.S. ( 2011). Clinical spectrum of bacteraemic Fusobacterium infections: from septic shock to nosocomial bacteraemia. Scand J Infect Dis 43:463–470 [CrossRef]
    [Google Scholar]
  23. Rubinstein E., Onderdonk A.B., Rahal J.J. Jr ( 1974). Peritonsillar infection and bacteremia caused by Fusobacterium gonidiaformans. . J Pediatr 85:673–675 [CrossRef]
    [Google Scholar]
  24. Yang C‐C., Ye J‐J., Hsu P‐C., Chang H‐J., Cheng C‐W., Leu H‐S., Chiang P‐C., Lee M‐H. ( 2011). Characteristics and outcomes of Fusobacterium nucleatum bacteremia – a 6‐year experience at a tertiary care hospital in northern Taiwan. Diagn Microbiol Infect Dis 70:167–174 [CrossRef]
    [Google Scholar]
/content/journal/jmmcr/10.1099/jmmcr.0.002139
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error