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JMM Case Reports JMM Case Reports

Volume 1, Issue 3

Fatal cryptococcal meningitis in a HIV‐seronegative patient with liver cirrhosis Open Access

Abstract

Introduction:

A 41‐year‐old man with a history of alcoholic cirrhosis presented to Patan Hospital in Kathmandu, Nepal, with a severe headache.

Case presentation:

Clinical examination found an isolated sixth nerve palsy of the left side with normal blood parameters and a normal brain scan. An initial cerebrospinal fluid analysis found lymphocytosis, with a significantly elevated protein level and reduced glucose. Tubercular meningitis was considered; however, the patient did not improve and a re‐examination of the cerebrospinal fluid confirmed cryptococcal meningitis.

Conclusion:

After diagnosis the patient was treated with amphotericin B. Despite all efforts the patient died 5 days later.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): amphotericin B , cirrhosis , cryptococcal antigen lateral flow assay , headache and meningitis
© 2014 The Authors
  • This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/).
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/content/journal/jmmcr/10.1099/jmmcr.0.001982
2014-09-01
2025-07-18
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