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Mycobacterium simiae can cause disseminated infection in human immunodeficiency virus (HIV)‐infected patients, mainly with involvement of pulmonary and reticulo‐endothelial systems. Although this organism is also known to cause infections in non‐HIV‐infected individuals, to our knowledge there has been no report of pericardial effusion caused by M. simiae.
We describe a case report with massive pericardial effusion caused by M. simiae in a non‐HIV‐infected female patient, who presented with complaints of gradually increasing breathlessness and cough over a period of 1 month. Acid‐fast bacilli were isolated from the pericardial effusion and subsequently confirmed as M. simiae by PCR‐RFLP.
In an area where Mycobacterium tuberculosis infection is endemic, clinicians and microbiologists must be aware of the possibility of a non‐tubercular mycobacterial infection that could be misdiagnosed as a tubercular infection.
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