Catheter‐related bloodstream infection caused by in a bone‐marrow transplant patient: case report and review of the literature Open Access

Abstract

Introduction:

spp. are a rare but recognized cause of bloodstream infections (BSIs), particularly catheter‐related BSIs (CR‐BSI). These infections are mostly associated with long‐term central catheters and occur in immunocompromised patients. Their optimal management is still uncertain due to the paucity of cases.

Case presentation:

We describe a case of CR‐BSI by in a bone‐marrow transplant patient. Definitive diagnosis of the CR‐BSI was confirmed by using the differential time to positivity of blood cultures. The patient was treated with antibiotic therapy without catheter removal and the infection cleared despite the presence of persistent bacteraemia.

Conclusion:

Although in the present case report persistent CR‐BSI bacteraemia by cleared without catheter removal, further experience is required to confirm that these infections can, in some cases, be successfully treated while retaining the catheter.

Loading

Article metrics loading...

/content/journal/jmmcr/10.1099/jmmcr.0.001032
2014-09-01
2024-03-28
Loading full text...

Full text loading...

/deliver/fulltext/jmmcr/1/3/jmmcr001032.html?itemId=/content/journal/jmmcr/10.1099/jmmcr.0.001032&mimeType=html&fmt=ahah

References

  1. Aoyama K., Yingqian K., Katsukiyo Y., Tohru G., Katsuhiko K., Yuzuru M. ( 2009). Characterization of clinical isolates of Gordonia species in Japanese clinical samples during 1998–2008. Mycopathologia 168:165–183 [CrossRef]
    [Google Scholar]
  2. Arenskötter M., Bröker D., Steinbüchel A. ( 2004). Biology of the metabolically diverse genus Gordonia . Appl Environ Microbiol 70:3195–3204 [CrossRef]
    [Google Scholar]
  3. Blanc V., Dalle M., Markarian A., Debunne M.V., Duplay E., Rodriguez‐Nava V., Boiron P. ( 2007). Gordonia terrae: a difficult‐to‐diagnose emerging pathogen?. J Clin Microbiol 45:1076–1077 [CrossRef]
    [Google Scholar]
  4. Blaschke A.J., Bender J., Byington C.L., Korgenski K., Daly J., Petti C.A., Pavia A.T., Ampofo K. ( 2007). Gordonia species: emerging pathogens in pediatric patients that are identified by 16S ribosomal RNA gene sequencing. Clin Infect Dis 45:483–486 [CrossRef]
    [Google Scholar]
  5. Brust J.C., Whittier S., Scully B.E., McGregor C.C., Yin M.T. ( 2009). Five cases of bacteraemia due to Gordonia species. J Med Microbiol 58:1376–1378 [CrossRef]
    [Google Scholar]
  6. Buchman A.L., McNeil M.M., Brown J.M., Lasker B.A., Ament M.E. ( 1992). Central venous catheter sepsis caused by unusual Gordona ( Rhodococcus) species: identification with a digoxigenin‐labeled rDNA probe. Clin Infect Dis 15:694–697 [CrossRef]
    [Google Scholar]
  7. CLSI( 2011). Susceptibility Testing of Mycobacteria, Nocardiae and Other Aerobic Actinomycetes; Approved Standard M24‐A2 Wayne, PA: Clinical and Laboratory Standards Institute;
    [Google Scholar]
  8. Diamantis P., Valachis A., Scoulica E., Christidou A., Maraki S., Samonis G. ( 2012). Hickman catheter‐related bacteremia caused by Gordonia sputi in a patient with breast cancer. J Infect Dev Ctries 6:188–191
    [Google Scholar]
  9. Gil‐Sande E., Brun‐Otero M., Campo‐Cerecedo F., Esteban E., Aguilar L., Garcia‐de‐Lomas J. ( 2006). Etiological misidentification by routine biochemical tests of bacteremia caused by Gordonia terrae infection in the course of an episode of acute cholecystitis. J Clin Microbiol 44:2645–2647 [CrossRef]
    [Google Scholar]
  10. Grisold A.J., Roll P., Hoenigl M., Vicenzi‐Moser R., Marth E. ( 2007). Isolation of Gordonia terrae from a patient with catheter‐related bacteraemia. J Med Microbiol 56:1687–1688 [CrossRef]
    [Google Scholar]
  11. Gupta M., Prasad D., Khara H.S., Alcid D. ( 2010). A rubber‐degrading organism growing from a human body. Int J Infect Dis 14:75–76 [CrossRef]
    [Google Scholar]
  12. Johnson J.A., Onderdonk A.B., Cosimi L.A., Yawetz S., Lasker B.A., Bolcen S.J., Brown J.M., Marty F.M. ( 2011). Gordonia bronchialis bacteremia and pleural infection: case report and review of the literature. J Clin Microbiol 49:1662–1666 [CrossRef]
    [Google Scholar]
  13. Kempf V.A., Schmalzing M., Yassin A.F., Schaal K.P., Baumeister D., Arenskötter M., Steinbüchel A., Autenriet I.B. ( 2004). Gordonia polyisoprenivorans septicemia in a bone marrow transplant patient. Eur J Clin Microbiol Infect Dis 23:226–228 [CrossRef]
    [Google Scholar]
  14. Kuwabara M., Onitsuka T., Nakamura K., Shimada M., Ohtaki S., Mikami Y. ( 1999). Mediastinitis due to Gordona sputi after CABG. J Cardiovasc Surg 40:675–677
    [Google Scholar]
  15. Lai C.C., Wang C.Y., Liu C.Y., Tan C.K., Lin S.H., Liao C.H., Chou C.H., Huamg Y.T., Lin H.I., Hsueh P.R. ( 2010). Infections caused by Gordonia species at a medical centre in Taiwan, 1997 to 2008. Clin Microbiol Infect 16:1448–1453 [CrossRef]
    [Google Scholar]
  16. Lesens O., Hansmann Y., Riegel P., Heller R., Benaissa‐Djellouli M., Martinot M., Petit H., Christmann D. ( 2000). Bacteremia and endocarditis caused by a Gordonia species in a patient with a central venous catheter. Emerg Infect Dis 6:382–385 [CrossRef]
    [Google Scholar]
  17. Moser B.D., Pellegrini G.J., Lasker B.A., Brown J.M. ( 2012). Pattern of antimicrobial susceptibility obtained from blood isolates a rare but emerging human pathogen, Gordonia polyisoprenivorans . Antimicrob Agents Chemother 56:4991–4993 [CrossRef]
    [Google Scholar]
  18. Siddiqui N., Toumeh A., Georgescu C. ( 2012). Tibial osteomyelitis caused by Gordonia bronchialis in an immunocompetent patient. J Clin Microbiol 50:3119–3121 [CrossRef]
    [Google Scholar]
  19. Pham A.S., I., Rolston K.V., Tarrand J.J., Han X.Y. ( 2003). Catheter‐related bacteremia caused by the nocardioform actinomycete Gordonia terrae . Clin Infect Dis 36:524–527 [CrossRef]
    [Google Scholar]
  20. Renvoise A., Harle J.R., Raoul D., Roux V. ( 2009). Gordonia sputi bacteremia. Emerg Infect Dis 15:1535–1537 [CrossRef]
    [Google Scholar]
  21. Richet H.M., Craven P.C., Brown J.M., Lasker B.A., Cox C.D., McNeil M.M., Tice A.D., Jarvis W.R., Tablan O.C. ( 1991). A cluster of Rhodococcus ( Gordona) bronchialis sternal‐wound infections after coronary‐artery bypass surgery. N Engl J Med 324:104–109 [CrossRef]
    [Google Scholar]
  22. Riegel P., Ruimy R., de Briel D., Eichler F., Bergerat J.P., Christen R., Monteil H. ( 1996). Bacteremia due to Gordona sputi in an immunocompromised patient. J Clin Microbiol 34:2045–2047
    [Google Scholar]
  23. Shen F.T., Lu H.L., Lin J.L., Huang W.S., Arun A.B., Young C.C. ( 2006). Phylogenetic analysis of members of the metabolically diverse genus Gordonia based on proteins encoding the gyrB gene. Res Microbiol 157:367–375 [CrossRef]
    [Google Scholar]
  24. Sng L.H., Koh T.H., Toney S.R., Floyd M., Butler W.R., Tan B.H. ( 2004). Bacteremia caused by Gordonia bronchialis in a patient with sequestrated lung. J Clin Microbiol 42:2870–2871 [CrossRef]
    [Google Scholar]
  25. Verma P., Brown J.M., Nunez V.H., Morey R.E., Steigerwalt A.G., Pellegrini G.J., Kessler H.A. ( 2006). Native valve endocarditis due to Gordonia polyisoprenivorans: case report and review of literature of bloodstream infections caused by Gordonia species. J Clin Microbiol 44:1905–1908 [CrossRef]
    [Google Scholar]
  26. Werno A.M., Anderson T.P., Chambers S.T., Laird H.M., Murdoch D.R. ( 2005). Recurrent breast abscess caused by Gordonia bronchialis in an immunocompetent patient. J Clin Microbiol 43:3009–3010 [CrossRef]
    [Google Scholar]
  27. Zardawi I.M., Jones F., Clark D.A., Holland J. ( 2004). Gordonia terrae‐induced suppurative granulomatous mastitis following nipple piercing. Pathology 36:275–278 [CrossRef]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmmcr/10.1099/jmmcr.0.001032
Loading
/content/journal/jmmcr/10.1099/jmmcr.0.001032
Loading

Data & Media loading...

Most cited Most Cited RSS feed