Gordonia spp. are a rare but recognized cause of bloodstream infections (BSIs), particularly catheter‐related BSIs (CR‐BSI). These infections are mostly associated with long‐term central catheters and occur in immunocompromised patients. Their optimal management is still uncertain due to the paucity of cases.
Case presentation:
We describe a case of CR‐BSI by Gordonia terrae in a bone‐marrow transplant patient. Definitive diagnosis of the CR‐BSI was confirmed by using the differential time to positivity of blood cultures. The patient was treated with antibiotic therapy without catheter removal and the infection cleared despite the presence of persistent bacteraemia.
Conclusion:
Although in the present case report persistent CR‐BSI bacteraemia by G. terrae cleared without catheter removal, further experience is required to confirm that these infections can, in some cases, be successfully treated while retaining the catheter.
AoyamaK.,
YingqianK.,
KatsukiyoY.,
TohruG.,
KatsuhikoK.,
YuzuruM.(2009). Characterization of clinical isolates of Gordonia species in Japanese clinical samples during 1998–2008. Mycopathologia 168:165–183[CrossRef]
BrustJ.C.,
WhittierS.,
ScullyB.E.,
McGregorC.C.,
YinM.T.(2009). Five cases of bacteraemia due to Gordonia species. J Med Microbiol 58:1376–1378[CrossRef]
CLSI(2011).Susceptibility Testing of Mycobacteria, Nocardiae and Other Aerobic Actinomycetes; Approved Standard M24‐A2 Wayne, PA: Clinical and Laboratory Standards Institute;
DiamantisP.,
ValachisA.,
ScoulicaE.,
ChristidouA.,
MarakiS.,
SamonisG.(2012). Hickman catheter‐related bacteremia caused by Gordonia sputi in a patient with breast cancer. J Infect Dev Ctries 6:188–191
Gil‐SandeE.,
Brun‐OteroM.,
Campo‐CerecedoF.,
EstebanE.,
AguilarL.,
Garcia‐de‐LomasJ.(2006). Etiological misidentification by routine biochemical tests of bacteremia caused by Gordonia terrae infection in the course of an episode of acute cholecystitis. J Clin Microbiol 44:2645–2647[CrossRef]
GrisoldA.J.,
RollP.,
HoeniglM.,
Vicenzi‐MoserR.,
MarthE.(2007). Isolation of Gordonia terrae from a patient with catheter‐related bacteraemia. J Med Microbiol 56:1687–1688[CrossRef]
JohnsonJ.A.,
OnderdonkA.B.,
CosimiL.A.,
YawetzS.,
LaskerB.A.,
BolcenS.J.,
BrownJ.M.,
MartyF.M.(2011).Gordonia bronchialis bacteremia and pleural infection: case report and review of the literature. J Clin Microbiol 49:1662–1666[CrossRef]
LaiC.C.,
WangC.Y.,
LiuC.Y.,
TanC.K.,
LinS.H.,
LiaoC.H.,
ChouC.H.,
HuamgY.T.,
LinH.I.,
HsuehP.R.(2010). Infections caused by Gordonia species at a medical centre in Taiwan, 1997 to 2008. Clin Microbiol Infect 16:1448–1453[CrossRef]
LesensO.,
HansmannY.,
RiegelP.,
HellerR.,
Benaissa‐DjellouliM.,
MartinotM.,
PetitH.,
ChristmannD.(2000). Bacteremia and endocarditis caused by a Gordonia species in a patient with a central venous catheter. Emerg Infect Dis 6:382–385[CrossRef]
MoserB.D.,
PellegriniG.J.,
LaskerB.A.,
BrownJ.M.(2012). Pattern of antimicrobial susceptibility obtained from blood isolates a rare but emerging human pathogen, Gordonia polyisoprenivorans
. Antimicrob Agents Chemother 56:4991–4993[CrossRef]
RiegelP.,
RuimyR.,
de BrielD.,
EichlerF.,
BergeratJ.P.,
ChristenR.,
MonteilH.(1996). Bacteremia due to Gordona sputi in an immunocompromised patient. J Clin Microbiol 34:2045–2047
ShenF.T.,
LuH.L.,
LinJ.L.,
HuangW.S.,
ArunA.B.,
YoungC.C.(2006). Phylogenetic analysis of members of the metabolically diverse genus Gordonia based on proteins encoding the gyrB gene. Res Microbiol 157:367–375[CrossRef]
VermaP.,
BrownJ.M.,
NunezV.H.,
MoreyR.E.,
SteigerwaltA.G.,
PellegriniG.J.,
KesslerH.A.(2006). Native valve endocarditis due to Gordonia polyisoprenivorans: case report and review of literature of bloodstream infections caused by Gordonia species. J Clin Microbiol 44:1905–1908[CrossRef]
WernoA.M.,
AndersonT.P.,
ChambersS.T.,
LairdH.M.,
MurdochD.R.(2005). Recurrent breast abscess caused by Gordonia bronchialis in an immunocompetent patient. J Clin Microbiol 43:3009–3010[CrossRef]