1887

JMM Case Reports

Volume 2, Issue 5

prosthetic valve endocarditis in a patient with Marfan syndrome Open Access

Abstract

Introduction:

is a non-tuberculous mycobacterium ubiquitous in the environment, which rarely causes endovascular infections. We report the first published case, to the best of our knowledge, of endocarditis in a patient with Marfan syndrome.

Case presentation:

A female in her 40s with a history of Marfan syndrome status-post mechanical aortic valve replacement and a chronic indwelling venous access port presented with a 2-day history of confusion and 3-month history of intermittent fevers. Her blood cultures grew . An echocardiogram revealed a 1 cm vegetation attached to the prosthetic aortic valve and a perivalvular abscess. The patient was started on imipenem/cilastatin, amikacin and linezolid. Her course was complicated by septic emboli to the brain and subarachnoid haemorrhage. She was deemed a poor surgical candidate. The patient ultimately developed cardiac arrest and died.

Conclusion:

endocarditis is rare and is associated with high mortality. Late recognition of as a causative pathogen of endovascular infection, extensive antimicrobial resistance and limited surgical options at the time of diagnosis make the management of endocarditis very challenging.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): amikacin , imipenem/cilastatin infective endocarditis , linezolid , Marfan syndrome and non-tuberculous mycobacteria
© 2015 The Authors
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2015-10-09
2024-04-25
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